Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.35 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.32 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.32 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.31 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.31 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.31 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.31 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5078848 | 0.91 | ALDH1A1 (0.41) | TSHRALDH1A1PTPN1GSK3BMAPT | |
| SCHEMBL5079631 | 0.75 | ALDH1A1 (0.47) | TSHRALDH1A1GSK3BMAPTLMNA | |
| SCHEMBL17965795 | 0.71 | TSHR (0.50) | TSHRALDH1A1PTPN1GPR35MAPT | |
| SCHEMBL5080676 | 0.69 | TSHR (0.41) | TSHRALDH1A1GPR35GSK3BMAPT | |
| SCHEMBL25262181 | 0.68 | ALDH1A1 (0.47) | TSHRALDH1A1GPR35MAPTLMNA | |
| SCHEMBL28744988 | 0.68 | ALDH1A1 (0.47) | TSHRALDH1A1GPR35MAPTLMNA | |
| SCHEMBL27557396 | 0.68 | ALDH1A1 (0.47) | TSHRALDH1A1GPR35MAPTLMNA | |
| SCHEMBL5080682 | 0.68 | ALDH1A1 (0.51) | TSHRALDH1A1GPR35GSK3BMAPT | |
| SCHEMBL5078862 | 0.66 | FHIT (0.50) | TSHRALDH1A1GPR35MAPTLMNA | |
| SCHEMBL21612061 | 0.65 | MAPT (0.46) | TSHRALDH1A1MAPTLMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1678218-A1 | COMPONENTS AND CATALYSTS FOR THE POLYMERIZATION OF OLEFINS | Basell Poliolefine Italia S.r.l. (IT) | 2006-07-12 | — | — | EP | disclosed |
| WO-2005047351-A1 | COMPONENTS AND CATALYSTS FOR THE POLYMERIZATION OF OLEFINS | BASELL POLIOLEFINE ITALIA S.R.L. (IT) | 2005-05-26 | — | — | WO | disclosed |