SCHEMBL5080236

SCHEMBL5080236

Nc1cc(F)c(N)c(F)c1

nearest known ligand 0.42

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
HDAC1 Q13547 1/20 0.42
HDAC6 Q9UBN7 1/20 0.42
ALDH1A1 P00352 3/20 0.40
CYP3A4 P08684 3/20 0.40
GAA P10253 1/20 0.40
MAPT P10636 1/20 0.40
TSHR P16473 1/20 0.37
CA1 P00915 3/20 0.36
CA2 P00918 3/20 0.36
CA9 Q16790 3/20 0.36
TP53 P04637 1/20 0.35
CA3 P07451 1/20 0.34
ADRA2B P18089 1/20 0.32
THRB P10828 1/20 0.30
KIF11 P52732 1/20 0.30
CASP1 P29466 1/20 0.30
RECQL P46063 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20843494 0.80 ALDH1A1 (0.43) HDAC1HDAC6ALDH1A1CYP3A4GAA
SCHEMBL113484 0.79 ALDH1A1 (0.48) HDAC1HDAC6ALDH1A1MAPTCA1
SCHEMBL8395028 0.79 CYP3A4 (0.42) ALDH1A1CYP3A4GAAMAPTTSHR
SCHEMBL9001391 0.79 HDAC1 (0.42) HDAC1HDAC6ALDH1A1CYP3A4TSHR
SCHEMBL111459 0.79 CES2 (0.41) ALDH1A1CYP3A4GAAMAPTTSHR
Iodide SCHEMBL30689240 0.76 CES2 (0.39) ALDH1A1CYP3A4GAAMAPTTSHR
Bromide SCHEMBL31241400 0.76 CES2 (0.39) ALDH1A1CYP3A4GAAMAPTTSHR
SCHEMBL22889966 0.74
SCHEMBL2140713 0.73 CYP3A4 (0.45) HDAC1HDAC6ALDH1A1CYP3A4GAA
SCHEMBL2360976 0.73 ALDH1A1 (0.33) ALDH1A1CYP3A4GAAMAPTTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 81 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250346020-A1 LAMINATE AND DISPLAY KANEKA CORPORATION (JP) 2025-11-13 US disclosed
US-20250320338-A1 TRANSPARENT FILM, HARD COAT FILM, AND DISPLAY KANEKA CORPORATION (JP) 2025-10-16 US disclosed
CN-119948089-A Hard coating film and display 株式会社钟化 2025-05-06 CN disclosed
US-20250109264-A1 FILM, METHOD FOR MANUFACTURING SAME, AND IMAGE DISPLAY DEVICE KANEKA CORPORATION (JP) 2025-04-03 US disclosed
US-12234323-B2 Transparent polyimide film and production method therefor KANEKA CORPORATION (JP) 2025-02-25 US disclosed
US-20240392131-A1 RESIN COMPOSITION, MOLDED BODY, AND FILM KANEKA CORPORATION (JP) 2024-11-28 US disclosed
CN-118974146-A Film, method for producing the same, and image display device 株式会社钟化 2024-11-15 CN disclosed
WO-2024172021-A1 HARD COATING FILM, METHOD FOR PRODUCING SAME, AND DISPLAY 株式会社カネカ 2024-08-22 WO disclosed
CN-117279780-B Laminated substrate, laminated body manufacturing method, laminated body with member for electronic device, and electronic device manufacturing method AGC株式会社 2024-08-16 CN disclosed
WO-2024166911-A1 LAMINATE AND DISPLAY 株式会社カネカ 2024-08-15 WO disclosed
US-20150011726-A1 DIAMINE, POLYIMIDE, AND POLYIMIDE FILM AND UTILIZATION THEREOF TOHO UNIVERSITY (JP) 2015-01-08 US disclosed
WO-2013098373-A1 NEW AZETIDINE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS AND USES THEREOF BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2013-07-04 WO disclosed
US-8466252-B2 Optical film, optical film manufacturing method, transparent substrate, image display device, and solar cell KANEKA CORPORATION (JP) 2013-06-18 US disclosed
US-20120270999-A1 OPTICAL FILM, OPTICAL FILM MANUFACTURING METHOD, TRANSPARENT SUBSTRATE, IMAGE DISPLAY DEVICE, AND SOLAR CELL KANEKA CORPORATION (JP) 2012-10-25 US disclosed
US-20080124534-A1 Polyamide, Film, and Image Display Device FUJIFILM CORPORATION (JP) 2008-05-29 US disclosed
US-7208559-B2 Ethylened polymer and molded object obtained therefrom MITSUI CHEMICALS, INC. (JP) 2007-04-24 US disclosed
US-20060135712-A1 Ethylened polymer and molded object obtained therefrom MITSUI CHEMICALS, INC. (JP) 2006-06-22 US disclosed
EP-0718666-B1 Liquid crystal-aligning agent JSR CORP (JP) 2003-03-26 EP disclosed
US-5698135-A POLYAMIC ACID OBTAINED FROM REACTION OF DIANHYDRIDE OF SPECIFIED TETRACARBOXYLIC ACID AND OF CYCLOBUTANETETRACARBOXYLIC ACID WITH DIAMINE, OR POLYMER OBTAINED BY IMIDIZING SAID POLYAMIC ACID JAPAN SYNTHETIC RUBBER CO., LTD., A JAPANESE CORPORATION (JP) 1997-12-16 US disclosed
EP-0718666-A1 Liquid crystal-aligning agent JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1996-06-26 EP disclosed