Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.37 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | FHIT | P49789 | 1/20 | 0.35 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.35 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | NGFR | P08138 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8304526 | 0.86 | POLB (0.52) | DAOALDH1A1KDM4EMEN1MAPT | |
| SCHEMBL24264546 | 0.82 | GPR35 (0.47) | DAOALDH1A1KDM4EMEN1MAPT | |
| SCHEMBL11166197 | 0.82 | KDM4E (0.38) | DAOALDH1A1KDM4EMEN1MAPT | |
| SCHEMBL12768624 | 0.82 | POLB (0.36) | DAOALDH1A1KDM4EMEN1MAPT | |
| SCHEMBL9375730 | 0.78 | ALDH1A1 (0.42) | DAOALDH1A1KDM4EMEN1MAPT | |
| SCHEMBL26784147 | 0.78 | ALDH1A1 (0.44) | ALDH1A1KDM4EMEN1MAPTKMT2A | |
| SCHEMBL12111477 | 0.78 | GRIN2C (0.37) | DAOALDH1A1KDM4EMEN1MAPT | |
| SCHEMBL18357869 | 0.76 | GPR35 (0.47) | DAOALDH1A1KDM4EMEN1MAPT | |
| SCHEMBL20482165 | 0.75 | POLB (0.33) | DAOALDH1A1KDM4EMEN1MAPT | |
| SCHEMBL5727379 | 0.75 | GPR35 (0.42) | DAOALDH1A1KDM4EMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117304459-B | Bio-based sulfur-containing high-refraction polyester and preparation method and application thereof | 中国科学院宁波材料技术与工程研究所 | 2024-04-19 | — | — | CN | claimed |
| CN-117304459-A | Bio-based sulfur-containing high-refraction polyester and preparation method and application thereof | 中国科学院宁波材料技术与工程研究所 | 2023-12-29 | — | — | CN | claimed |
| CN-119176892-A | Ziegler-Navigator catalyst | 中国科学院大连化学物理研究所 | 2024-12-24 | — | — | CN | disclosed |
| CN-117304459-B | Bio-based sulfur-containing high-refraction polyester and preparation method and application thereof | 中国科学院宁波材料技术与工程研究所 | 2024-04-19 | — | — | CN | disclosed |
| CN-117304459-A | Bio-based sulfur-containing high-refraction polyester and preparation method and application thereof | 中国科学院宁波材料技术与工程研究所 | 2023-12-29 | — | — | CN | disclosed |
| US-20230312599-A1 | ALDOSE REDUCTASE INHIBITORS AND METHODS OF USE THEREOF | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK | 2023-10-05 | — | — | US | disclosed |
| US-7371802-B2 | Components and catalysts for the polymerization of olefins | BASELL POLIOLEFINE ITALIA S.R.L. (IT) | 2008-05-13 | — | — | US | disclosed |
| US-20070106039-A1 | Components and catalysts for the polymerization of olefins | BASELL POLIOLEFINE ITALIA S.R.L. (IT) | 2007-05-10 | — | — | US | disclosed |
| EP-1678218-A1 | COMPONENTS AND CATALYSTS FOR THE POLYMERIZATION OF OLEFINS | Basell Poliolefine Italia S.r.l. (IT) | 2006-07-12 | — | — | EP | disclosed |
| WO-2005047351-A1 | COMPONENTS AND CATALYSTS FOR THE POLYMERIZATION OF OLEFINS | BASELL POLIOLEFINE ITALIA S.R.L. (IT) | 2005-05-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230312599-A1 | ALDOSE REDUCTASE INHIBITORS AND METHODS OF USE THEREOF | ALDOA, AKR1B1, AKR1C2 | DAO 1785/4885ALDH1A1 23/4885KDM4E 2144/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.