SCHEMBL8304526

SCHEMBL8304526

Cc1sc(C)c(C(=O)O)c1C

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 4/20 0.52
RECQL P46063 1/20 0.52
ABCC1 P33527 3/20 0.43
MAPT P10636 6/20 0.42
ALDH1A1 P00352 5/20 0.42
LMNA P02545 2/20 0.42
GRIN2C Q14957 1/20 0.41
ALOX12 P18054 1/20 0.41
L3MBTL1 Q9Y468 3/20 0.38
KMT2A Q03164 3/20 0.38
MEN1 O00255 2/20 0.38
DAO P14920 2/20 0.38
KDM4E B2RXH2 1/20 0.38
PLA2G1B P04054 1/20 0.38
HPGD P15428 1/20 0.38
MAPK1 P28482 1/20 0.38
ATG4B Q9Y4P1 1/20 0.38
GPR35 Q9HC97 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
NPC1 O15118 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5080674 0.86 DAO (0.42) POLBRECQLABCC1MAPTALDH1A1
SCHEMBL18357869 0.80 GPR35 (0.47) POLBRECQLABCC1MAPTALDH1A1
SCHEMBL19712781 0.80 ALDH1A1 (0.40) POLBRECQLABCC1MAPTALDH1A1
SCHEMBL12205416 0.79 ALDH1A1 (0.38) POLBRECQLABCC1MAPTALDH1A1
SCHEMBL5727379 0.78 GPR35 (0.42) POLBRECQLABCC1MAPTALDH1A1
SCHEMBL3497284 0.78 ALDH1A1 (0.61) POLBRECQLABCC1MAPTALDH1A1
SCHEMBL3228565 0.78 POLB (0.47) POLBRECQLABCC1MAPTALDH1A1
SCHEMBL14364074 0.77 KMT2A (0.53) POLBMAPTALDH1A1LMNAGRIN2C
SCHEMBL24264546 0.75 GPR35 (0.47) POLBRECQLMAPTALDH1A1L3MBTL1
SCHEMBL12768624 0.75 POLB (0.36) POLBRECQLABCC1MAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0695748-B1 Tetrazolinone herbicides BAYER AGROCHEM KK (JP) 1999-05-06 EP disclosed
US-5589439-A HERBICIDES NIHON BAYER AGROCHEM K.K. (JP) 1996-12-31 US disclosed
EP-0695748-A1 Tetrazolinone herbicides NIHON BAYER AGROCHEM K.K. (JP) 1996-02-07 EP disclosed