Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 6/20 | 0.39 |
| ▸ | HPGD | P15428 | 5/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 3/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | XIAP | P98170 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | FHIT | P49789 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8201854 | 0.82 | FHIT (0.49) | ALDH1A1KDM4ECYP1A2MAPTHPGD | |
| SCHEMBL5080674 | 0.78 | DAO (0.42) | ALDH1A1KDM4ECYP1A2MAPTHPGD | |
| SCHEMBL29180339 | 0.77 | ALDH1A1 (0.38) | ALDH1A1KDM4ECYP1A2HSD17B10RECQL | |
| SCHEMBL27932259 | 0.75 | ALDH1A1 (0.37) | ALDH1A1KDM4ECYP1A2HSD17B10SMN1; SMN2 | |
| SCHEMBL8573447 | 0.73 | ALDH1A1 (0.39) | ALDH1A1CYP1A2HSD17B10NOTUMNPSR1 | |
| SCHEMBL1009054 | 0.73 | ALDH1A1 (0.39) | ALDH1A1CYP1A2HSD17B10NOTUMNPSR1 | |
| SCHEMBL13343473 | 0.73 | ALDH1A1 (0.36) | ALDH1A1KDM4ECYP1A2HSD17B10RECQL | |
| SCHEMBL13711828 | 0.73 | ALDH1A1 (0.50) | ALDH1A1KDM4ECYP1A2MAPTHPGD | |
| SCHEMBL17452191 | 0.72 | CYP1A2 (0.34) | ALDH1A1KDM4ECYP1A2MAPTHPGD | |
| SCHEMBL8304526 | 0.72 | POLB (0.52) | ALDH1A1KDM4EMAPTHPGDMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230365582-A1 | NOVEL COMPOUNDS HAVING INHIBITORY ACTIVITY ON PROSTAGLANDIN E2 RECEPTOR AND USES THEREOF | KANAPH THERAPEUTICS INC. (KR) | 2023-11-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230365582-A1 | NOVEL COMPOUNDS HAVING INHIBITORY ACTIVITY ON PROSTAGLANDIN E2 RECEPTOR AND USES THEREOF | PTGER1, PTGIR, PTGDR2 | ALDH1A1 1126/4885KDM4E 4594/4885CYP1A2 747/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.