Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 1/20 | 0.51 |
| ▸ | ACVR1B | P36896 | 3/20 | 0.50 |
| ▸ | TGFBR1 | P36897 | 3/20 | 0.50 |
| ▸ | KDM6B | O15054 | 1/20 | 0.48 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | PIM1 | P11309 | 1/20 | 0.45 |
| ▸ | BAD | Q92934 | 1/20 | 0.45 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.45 |
| ▸ | NAMPT | P43490 | 2/20 | 0.44 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.43 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.43 |
| ▸ | ACVRL1 | P37023 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12261505 | 0.90 | TGFBR1 (0.60) | CNR2ACVR1BTGFBR1KMT2AMEN1 | |
| SCHEMBL19523059 | 0.82 | TGFBR1 (0.53) | CNR2ACVR1BTGFBR1KDM6BKDM4C | |
| SCHEMBL12261441 | 0.81 | MKNK1 (0.44) | ACVR1BTGFBR1KDM6BKDM4CGAA | |
| SCHEMBL5083535 | 0.80 | CNR2 (0.51) | CNR2ACVR1BTGFBR1KDM4CNAMPT | |
| SCHEMBL24598453 | 0.79 | TP53 (0.57) | ACVR1BTGFBR1KDM6BKDM4CKMT2A | |
| SCHEMBL5078982 | 0.78 | L3MBTL1 (0.57) | CNR2KMT2AGAASMN1; SMN2POLB | |
| SCHEMBL28064903 | 0.77 | MEN1 (0.42) | ACVR1BTGFBR1KDM4CKMT2AMEN1 | |
| SCHEMBL24598472 | 0.77 | TP53 (0.60) | KDM6BKDM4CKMT2AMEN1POLB | |
| SCHEMBL4582070 | 0.75 | KDM4C (0.50) | ACVR1BTGFBR1KDM6BKDM4CKMT2A | |
| SCHEMBL3818665 | 0.75 | SIRT3 (0.43) | ACVR1BTGFBR1KDM6BKDM4CSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080132505-A1 | Combination Of Cb2 Modulators And Pde4 Inhibitors For Use In Medicine | GLAXO GROUP LIMITED | 2008-06-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080132505-A1 | Combination Of Cb2 Modulators And Pde4 Inhibitors For Use In Medicine | CNR2, CNR1, PDE4A | CNR2 1/4885ACVR1B 1087/4885TGFBR1 1308/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.