SCHEMBL5080892

SCHEMBL5080892

CC(C)(CO[Si](C)(C)c1ccccc1)CO[Si](C)(C)c1ccccc1

nearest known ligand 0.33

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.33
ESR2 Q92731 1/20 0.33
MAPK1 P28482 1/20 0.32
NR1H2 P55055 2/20 0.32
NR1H3 Q13133 2/20 0.32
MAPT P10636 1/20 0.31
TAAR1 Q96RJ0 2/20 0.30
ALDH1A1 P00352 1/20 0.30
ALOX15 P16050 1/20 0.30
SLC6A2 P23975 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5077257 0.93 NUDT1 (0.35) ALOX15
SCHEMBL5080794 0.89 MAPK1 (0.31) MAPK1ALDH1A1
SCHEMBL5080809 0.87 LMNA (0.30)
SCHEMBL5081805 0.82 TSHR (0.33)
SCHEMBL5078703 0.81 DUT (0.38) ESR1ESR2MAPK1TAAR1ALDH1A1
SCHEMBL5080896 0.77 SLC6A2 (0.38) NR1H2NR1H3MAPTTAAR1SLC6A2
SCHEMBL5080756 0.76 NUDT1 (0.34)
SCHEMBL5078644 0.76 GAA (0.30)
SCHEMBL106512 0.76 ESR1 (0.37) ESR1ESR2MAPTALDH1A1
SCHEMBL5077762 0.75 NUDT1 (0.36) ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7323431-B2 Catalyst for olefin polymerization and use of the same CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2008-01-29 US claimed
US-20060142146-A1 Catalyst for olefin polymerization and use of the same CHINA PETROLEUM & CHEMICAL CORPORATION 2006-06-29 US claimed
US-7323431-B2 Catalyst for olefin polymerization and use of the same CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2008-01-29 US disclosed
US-20060142146-A1 Catalyst for olefin polymerization and use of the same CHINA PETROLEUM & CHEMICAL CORPORATION 2006-06-29 US disclosed