Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.68 |
| ▸ | MEN1 | O00255 | 5/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.67 |
| ▸ | TP53 | P04637 | 3/20 | 0.67 |
| ▸ | HTT | P42858 | 3/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.67 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.67 |
| ▸ | HPGD | P15428 | 1/20 | 0.67 |
| ▸ | TMPRSS4 | Q9NRS4 | 1/20 | 0.65 |
| ▸ | NPC1 | O15118 | 3/20 | 0.64 |
| ▸ | RAB9A | P51151 | 3/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.64 |
| ▸ | POLB | P06746 | 2/20 | 0.64 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.64 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.64 |
| ▸ | RELA | Q04206 | 1/20 | 0.64 |
| ▸ | PNLIP | P16233 | 2/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.57 |
| ▸ | PLAU | P00749 | 2/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18327174 | 0.86 | LMNA (0.89) | LMNAMEN1KMT2ATP53HTT | |
| SCHEMBL12700352 | 0.84 | HTT (0.71) | LMNAMEN1KMT2AHTTTMPRSS4 | |
| SCHEMBL12700388 | 0.84 | LMNA (0.57) | LMNAMEN1KMT2AHTTHPGD | |
| SCHEMBL12700249 | 0.84 | KMT2A (0.56) | LMNAMEN1KMT2AHTTTMPRSS4 | |
| SCHEMBL12163156 | 0.84 | LMNA (0.68) | LMNAMEN1KMT2ATP53HTT | |
| Salicylanilide SCHEMBL28260990 | 0.83 | MEN1 (0.96) | LMNAMEN1KMT2ATP53HTT | |
| Salicylanilide SCHEMBL11600049 | 0.83 | MEN1 (0.96) | LMNAMEN1KMT2ATP53HTT | |
| SCHEMBL13164045 | 0.83 | HPGD (0.68) | LMNAMEN1KMT2AHTTHPGD | |
| SCHEMBL15290401 | 0.83 | PTGS1 (0.60) | LMNAMEN1KMT2AHTTTMPRSS4 | |
| SCHEMBL28084401 | 0.83 | KMT2A (0.68) | LMNAMEN1KMT2AHTTTMPRSS4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10166237-B2 | Compounds and methods for inducing chondrogenesis | THE SCRIPPS RESEARCH INSTITUTE (US) | 2019-01-01 | — | — | US | disclosed |
| US-20170112843-A1 | COMPOUNDS AND METHODS FOR INDUCING CHONDROGENESIS | THE SCRIPPS RESEARCH INSTITUTE | 2017-04-27 | — | — | US | disclosed |
| US-9464065-B2 | Compounds and methods for inducing chondrogenesis | THE SCRIPPS RESEARCH INSTITUTE (US) | 2016-10-11 | — | — | US | disclosed |
| WO-2012129562-A2 | COMPOUNDS AND METHODS FOR INDUCING CHONDROGENESIS | THE SCRIPPS RESEARCH INSTITUTE (US) | 2012-09-27 | — | — | WO | disclosed |
| EP-1534657-B1 | PROCESS FOR PREPARING ALDEHYDE COMPOUNDS | INVISTA TECH SARL (CH) | 2008-10-08 | — | — | EP | disclosed |
| EP-1534657-A4 | PROCESS FOR PREPARING ALDEHYDE COMPOUNDS | INVISTA TECH SARL (US) | 2006-08-02 | — | — | EP | disclosed |
| EP-1534657-A1 | PROCESS FOR PREPARING ALDEHYDE COMPOUNDS | INVISTA Technologies S.à.r.l. (US) | 2005-06-01 | — | — | EP | disclosed |
| WO-2004020381-A1 | PROCESS FOR PREPARING ALDEHYDE COMPOUNDS | INVISTA TECHNOLOGIES S.À.R.L. (US) | 2004-03-11 | — | — | WO | disclosed |
| US-6664427-B1 | From an unsaturated compound by hydroformylation and in the presence of a catalyst system comprising a Group VIII metal and a bidentate phosphorus ligand having two trivalent phosphorus atoms bound to salicylanilide groups | E. I. DU PONT DE NEMOURS AND COMPANY | 2003-12-16 | — | — | US | disclosed |
| US-6358960-B1 | FOR THERAPY OF INTRAVASCULAR COAGULATION, CORONARY THROMBOSIS, CEREBRAL INFARCTION, CEREBRAL EMBOLISM, TRANSIENT ISCHEMIC ATTACK, CEREBROVASCULAR DISORDERS, PULMONARY VASCULAR DISEASES, DEEP VENOUS THROMBOSIS, ETC. | ONO PHARMACEUTICAL CO., LTD. (JP) | 2002-03-19 | — | — | US | disclosed |
| EP-1078917-A1 | AMIDINO DERIVATIVES AND DRUGS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO., LTD. (JP) | 2001-02-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10166237-B2 | Compounds and methods for inducing chondrogenesis | COL2A1, BMP4, BMP2 | LMNA 2285/4885MEN1 4660/4885KMT2A 3000/4885 |
| US-20170112843-A1 | COMPOUNDS AND METHODS FOR INDUCING CHONDROGENESIS | COL2A1, BMP4, BMP2 | LMNA 2285/4885MEN1 4660/4885KMT2A 3000/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.