SCHEMBL5081392

SCHEMBL5081392

O=C1C=CC(=O)N1c1cc(N2C(=O)C=CC2=O)c(Cl)cc1Cl

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 12/20 0.56
ALDH1A1 P00352 4/20 0.50
NPSR1 Q6W5P4 4/20 0.50
HSP90AA1 P07900 4/20 0.50
CCR6 P51684 3/20 0.50
PKM P14618 2/20 0.50
APOBEC3G Q9HC16 2/20 0.50
MAPT P10636 2/20 0.50
MAPK1 P28482 1/20 0.50
RAB9A P51151 1/20 0.50
CACNA1B Q00975 1/20 0.50
APBA1 Q02410 1/20 0.50
TLR9 Q9NR96 2/20 0.48
HTT P42858 3/20 0.41
LMNA P02545 2/20 0.41
HPGD P15428 2/20 0.41
MEN1 O00255 1/20 0.41
G6PD P11413 1/20 0.41
ALOX12 P18054 1/20 0.41
KMT2A Q03164 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10705507 0.93 MGLL (0.54) MGLLALDH1A1NPSR1HSP90AA1CCR6
SCHEMBL30645221 0.92 MGLL (0.58) MGLLALDH1A1NPSR1HSP90AA1CCR6
SCHEMBL30464215 0.78 MGLL (0.59) MGLLALDH1A1NPSR1HSP90AA1CCR6
SCHEMBL5075617 0.78 MGLL (0.59) MGLLALDH1A1NPSR1HSP90AA1CCR6
SCHEMBL9155405 0.78 MGLL (0.59) MGLLALDH1A1NPSR1HSP90AA1CCR6
SCHEMBL10587424 0.76 NPSR1 (0.57) MGLLALDH1A1NPSR1HSP90AA1CCR6
SCHEMBL10587456 0.76 MGLL (0.57) MGLLALDH1A1NPSR1HSP90AA1PKM
SCHEMBL26667212 0.76 MGLL (0.57) MGLLALDH1A1NPSR1HSP90AA1CCR6
SCHEMBL23388366 0.74 MGLL (0.55) MGLLALDH1A1NPSR1HSP90AA1CCR6
SCHEMBL9837527 0.74 MGLL (0.55) MGLLALDH1A1NPSR1HSP90AA1CCR6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 56 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5300585-A Having improved cure reversion THE GOODYEAR TIRE & RUBBER COMPANY (US) 1994-04-05 US claimed
US-12552908-B2 Thermally expandable compositions comprising a chemical blowing agent SIKA TECHNOLOGY AG (CH) 2026-02-17 US disclosed
US-11753522-B2 Use of magnesium oxide for crosslinking polymers ARKEMA FRANCE (FR) 2023-09-12 US disclosed
US-20220372238-A1 THERMALLY EXPANDABLE COMPOSITIONS COMPRISING A CHEMICAL BLOWING AGENT SIKA TECHNOLOGY AG (CH) 2022-11-24 US disclosed
EP-4039733-A1 METHODS FOR CROSSLINKING POLYMER COMPOSITIONS IN THE PRESENCE OF ATMOSPHERIC OXYGEN Arkema, Inc. (US) 2022-08-10 EP disclosed
EP-4013810-A1 THERMALLY EXPANDABLE COMPOSITIONS COMPRISING A CHEMICAL BLOWING AGENT Sika Technology AG (CH) 2022-06-22 EP disclosed
EP-2970605-B1 METHODS FOR CROSSLINKING POLYMER COMPOSITIONS IN THE PRESENCE OF ATMOSPHERIC OXYGEN ARKEMA INC (US) 2021-12-01 EP disclosed
WO-2021028599-A1 THERMALLY EXPANDABLE COMPOSITIONS COMPRISING A CHEMICAL BLOWING AGENT SIKA TECHNOLOGY AG (CH) 2021-02-18 WO disclosed
EP-3778734-A1 THERMALLY EXPANDABLE COMPOSITIONS COMPRISING A CHEMICAL BLOWING AGENT SIKA TECHNOLOGY AG (CH) 2021-02-17 EP disclosed
EP-2780413-B1 NANOSILICA CONTAINING POLYCYANATE ESTER RESIN COMPOSITIONS 3M INNOVATIVE PROPERTIES CO (US) 2019-09-25 EP disclosed
US-5262488-A Rubber for aging, tear resistance and tensile strength THE GOODYEAR TIRE & RUBBER COMPANY (US) 1993-11-16 US disclosed
EP-0564966-A2 A rubber vulcanization composition THE GOODYEAR TIRE & RUBBER COMPANY (US) 1993-10-13 EP disclosed
EP-0345825-B1 RUBBER COMPOSITION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1993-08-11 EP disclosed
US-5109055-A Blend with a dinitrodiamine compound with n-(cyclohexylthio)-phthalimide and(or) 2,3,5,6-tetrachloro-1,4-benzoqionone SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1992-04-28 US disclosed
EP-0410152-A1 Rubber composition having excellent dynamic properties SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1991-01-30 EP disclosed
US-4960833-A Rubber composition with nitrogen and phosphorous compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1990-10-02 US disclosed
EP-0191931-B1 RUBBER COMPOSITION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1990-07-04 EP disclosed
EP-0345825-A1 Rubber composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1989-12-13 EP disclosed
US-4803250-A AROMATIC CARBOXYLIC ANHYDRIDE, BISMALEIMIDE, SULFUR, ACCELERATOR, NONREVERTING, ANTICRACKING SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1989-02-07 US disclosed
EP-0191931-A2 Rubber composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1986-08-27 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12552908-B2 Thermally expandable compositions comprising a chemical blowing agent CA1, CA3, CA12 MGLL 2570/4885ALDH1A1 1546/4885NPSR1 3950/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.