Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.46 |
| ▸ | IDO1 | P14902 | 3/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | C1R | P00736 | 1/20 | 0.34 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
| ▸ | CDC7 | O00311 | 1/20 | 0.33 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
| ▸ | PNMT | P11086 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7942042 | 0.73 | ALDH1A1 (0.39) | IDO1PNMT | |
| SCHEMBL5486703 | 0.73 | IDO1 (0.52) | TAAR1IDO1CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL29437224 | 0.72 | — | — | |
| SCHEMBL1445634 | 0.72 | — | — | |
| SCHEMBL1066724 | 0.71 | TAAR1 (0.46) | TAAR1 | |
| SCHEMBL7609506 | 0.71 | TAAR1 (0.46) | TAAR1IDO1CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL2043471 | 0.69 | — | — | |
| SCHEMBL284465 | 0.69 | — | — | |
| SCHEMBL32679351 | 0.68 | CYP1A2 (0.52) | TAAR1CYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL1666987 | 0.68 | CYP1A2 (0.52) | TAAR1CYP1A2CYP2D6CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1417252-B1 | HIGH REFRACTIVE INDEX POLYSILOXANES AND THEIR PREPARATION | DOW CORNING (US) | 2015-07-01 | — | — | EP | disclosed |
| US-7429638-B2 | High refractive index polysiloxanes and their preparation | DOW CORNING LIMITED (GB) | 2008-09-30 | — | — | US | disclosed |
| US-7429638-B2 | High refractive index polysiloxanes and their preparation | DOW CORNING LIMITED (GB) | 2008-09-30 | — | — | US | disclosed |
| US-20040236057-A1 | High refractive index polysiloxanes and their preparation | DOW SILICONES CORPORATION | 2004-11-25 | — | — | US | disclosed |
| US-20040138399-A1 | Preparation of silicone resins | DOW CORNING CORPORATION | 2004-07-15 | — | — | US | disclosed |
| EP-1417252-A2 | HIGH REFRACTIVE INDEX POLYSILOXANES AND THEIR PREPARATION | Dow Corning Corporation (US) | 2004-05-12 | — | — | EP | disclosed |
| EP-1383823-A1 | PREPARATION OF SILICONE RESINS | Dow Corning Corporation (US) | 2004-01-28 | — | — | EP | disclosed |
| WO-2003011944-A2 | HIGH REFRACTIVE INDEX POLYSILOXANES AND THEIR PREPARATION | DOW CORNING CORPORATION (US) | 2003-02-13 | — | — | WO | disclosed |
| WO-2002081552-A1 | PREPARATION OF SILICONE RESINS | DOW CORNING CORPORATION (US) | 2002-10-17 | — | — | WO | disclosed |