SCHEMBL5082867

SCHEMBL5082867

COC(=O)C(Cc1ccccc1)C(C)OC(=O)c1ccccc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.61
MEN1 O00255 1/20 0.61
ALDH1A1 P00352 3/20 0.46
LMNA P02545 2/20 0.46
CA12 O43570 1/20 0.46
CA2 P00918 1/20 0.46
CA7 P43166 1/20 0.46
CA9 Q16790 1/20 0.46
CA14 Q9ULX7 1/20 0.46
GLA P06280 1/20 0.46
TSHR P16473 2/20 0.46
THRB P10828 1/20 0.46
CYP2C9 P11712 1/20 0.46
CYP2C19 P33261 1/20 0.46
HSD17B10 Q99714 1/20 0.46
SLC6A2 P23975 1/20 0.45
SLC6A3 Q01959 1/20 0.45
TDP1 Q9NUW8 1/20 0.45
RAB9A P51151 3/20 0.44
GAA P10253 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5083408 0.89 PDCD1 (0.49) KMT2AMEN1ALDH1A1LMNACA12
SCHEMBL5082842 0.87 MMP8 (0.48) KMT2AMEN1ALDH1A1LMNATSHR
SCHEMBL5941353 0.87 TSHR (0.50) KMT2AMEN1ALDH1A1LMNATSHR
SCHEMBL5082172 0.86 KMT2A (0.46) KMT2AMEN1ALDH1A1LMNACA12
SCHEMBL5941226 0.85 TSHR (0.49) KMT2AMEN1ALDH1A1LMNATSHR
SCHEMBL5086238 0.85 TSHR (0.49) KMT2AMEN1ALDH1A1LMNATSHR
SCHEMBL5082847 0.84 TSHR (0.47) KMT2AMEN1ALDH1A1LMNACA12
SCHEMBL17901410 0.83 MEN1 (0.65) KMT2AMEN1ALDH1A1CA12CA2
SCHEMBL5079977 0.83 LMNA (0.47) KMT2AMEN1ALDH1A1LMNATSHR
SCHEMBL10339292 0.81 KMT2A (0.65) KMT2AMEN1ALDH1A1LMNACA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1746110-B1 CATALYST COMPONENT FOR OLEFIN POLYMERIZATION REACTION AND CATALYST THEREOF CHINA PETROLEUM & CHEMICAL (CN) 2015-03-11 EP disclosed
CN-101759816-B Method for preparing a catalyst component for olefinic polymerization, and a catalyst component thereof CHINA PETROLEUM & CHEMICAL 2012-05-30 CN disclosed
CN-101759816-A Method for preparing a catalyst component for olefinic polymerization, and a catalyst component thereof CHINA PETROLEUM & CHEMICAL 2010-06-30 CN disclosed
CN-100429243-C Method for preparing catalyst constituent for olefinic polymerization CHINA PETROCHEMICAL CO LTD (CN) 2008-10-29 CN disclosed
CN-100429242-C Catalyst components for olefinic polyreaction and catalyst thereof CHINA PETROLEUM & CHEMICAL (CN) 2008-10-29 CN disclosed
US-7351778-B2 Catalyst component for olefin polymerization and catalyst comprising the same CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2008-04-01 US disclosed
CN-100348624-C Catalyst components for olefinic polyreaction and catalyst thereof CHINA PETROLEUM & CHEMICAL (CN) 2007-11-14 CN disclosed
EP-1746110-A1 CATALYST COMPONENT FOR OLEFIN POLYMERIZATION REACTION AND CATALYST THEREOF China Petroleum & Chemical Corporation (CN) 2007-01-24 EP disclosed
CN-1891722-A Method for preparing catalyst constituent for olefinic polymerization CHINA PETROCHEMICAL CO LTD (CN) 2007-01-10 CN disclosed
US-20060287446-A1 Catalyst component for olefin polymerization and catalyst comprising the same BEIJING RESEARCH INSTITUTE OF CHEMICAL INDUSTRY CHINA PETROLEUM & CHEMICAL COPORATION (CN) 2006-12-21 US disclosed
CN-1282670-C Catalyst components for olefinic polyreaction and catalyst thereof CHINA PETROLEUM & CHEMICAL (CN) 2006-11-01 CN disclosed
CN-1803863-A Catalyst components for olefinic polyreaction and catalyst thereof CHINA PETROLEUM & CHEMICAL (CN) 2006-07-19 CN disclosed
CN-1803862-A Catalyst components for olefinic polyreaction and catalyst thereof CHINA PETROLEUM & CHEMICAL (CN) 2006-07-19 CN disclosed
CN-1690090-A Catalyst components for olefinic polyreaction and catalyst thereof SINOPEC CORP (CN) 2005-11-02 CN disclosed