Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRK6 | P43250 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12809269 | 0.73 | GRK6 (0.31) | GRK6 | |
| SCHEMBL1740246 | 0.70 | GRK6 (0.33) | GRK6 | |
| SCHEMBL5500863 | 0.67 | — | — | |
| SCHEMBL447768 | 0.65 | GAA (0.33) | — | |
| SCHEMBL4471762 | 0.61 | — | — | |
| SCHEMBL3098903 | 0.60 | GRK6 (0.32) | GRK6 | |
| SCHEMBL451291 | 0.60 | GRK6 (0.32) | GRK6 | |
| SCHEMBL3093838 | 0.60 | GRK6 (0.41) | GRK6 | |
| SCHEMBL541987 | 0.60 | MEN1 (0.36) | GRK6 | |
| SCHEMBL4792502 | 0.59 | ALOX15 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1658298-B1 | PHOSPHORUS-CONTAINING IMIDAZOLINES AND METAL COMPLEXES THEREOF | SOLVIAS AG (CH) | 2008-03-26 | — | — | EP | disclosed |
| US-20070010493-A1 | Phospinite-imidazolines and metal complexes thereof | SOLVIAS AG (CH) | 2007-01-11 | — | — | US | disclosed |
| EP-1658298-A2 | NOVEL ORGANIC COMPOUNDS AND METAL COMPLEXES | Solvias AG (CH) | 2006-05-24 | — | — | EP | disclosed |
| WO-2005021562-A2 | PHOSPINITE-IMIDAZOLINES AND METAL COMPLEXES THEREOF | SOLVIAS AG (CH) | 2005-03-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070010493-A1 | Phospinite-imidazolines and metal complexes thereof | H1-0, H1-2, H1-3 | GRK6 2302/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.