Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 2/20 | 0.49 |
| ▸ | SRD5A2 | P31213 | 3/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | FLT1 | P17948 | 1/20 | 0.44 |
| ▸ | FLT4 | P35916 | 1/20 | 0.44 |
| ▸ | KDR | P35968 | 1/20 | 0.44 |
| ▸ | VCAM1 | P19320 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | ITGA1 | P56199 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5082308 | 0.98 | MMP2 (0.48) | MMP2SRD5A2MAPK1FLT1FLT4 | |
| SCHEMBL4365595 | 0.91 | MMP2 (0.49) | MMP2SRD5A2VCAM1KMT2ASMN1; SMN2 | |
| Potassium Ion SCHEMBL4535868 | 0.91 | MMP2 (0.49) | MMP2SRD5A2VCAM1KMT2ASMN1; SMN2 | |
| Potassium Ion SCHEMBL11586061 | 0.87 | VCAM1 (0.54) | MMP2SRD5A2VCAM1KMT2AITGA1 | |
| SCHEMBL250228 | 0.85 | MMP2 (0.50) | MMP2SRD5A2MAPK1FLT1FLT4 | |
| SCHEMBL5082310 | 0.83 | MMP2 (0.49) | MMP2SRD5A2MAPK1FLT1FLT4 | |
| SCHEMBL5082270 | 0.83 | MMP2 (0.49) | MMP2SRD5A2MAPK1FLT1FLT4 | |
| SCHEMBL941907 | 0.80 | MMP2 (0.63) | MMP2CA1CA2 | |
| SCHEMBL11332440 | 0.78 | MCL1 (0.53) | MAPK1HTTHPGD | |
| SCHEMBL31266402 | 0.78 | MCL1 (0.53) | MAPK1HTTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1497374-B1 | FILLER REINFORCED POLYETHER IMIDE RESIN COMPOSITION AND MOLDED ARTICLE THEREOF | GEN ELECTRIC (US) | 2008-08-13 | — | — | EP | disclosed |
| US-7244778-B2 | Filler reinforced polyether imide resin composition and molded article thereof | GENERAL ELECTRIC COMPANY (US) | 2007-07-17 | — | — | US | disclosed |
| US-20050131105-A1 | Filler reinforced polyether imide resin composition and molded article thereof | SHPP GLOBAL TECHNOLOGIES B.V. (NL) | 2005-06-16 | — | — | US | disclosed |
| EP-1497374-A1 | FILLER REINFORCED POLYETHER IMIDE RESIN COMPOSITION AND MOLDED ARTICLE THEREOF | GENERAL ELECTRIC COMPANY (US) | 2005-01-19 | — | — | EP | disclosed |
| WO-2003087226-A1 | FILLER REINFORCED POLYETHER IMIDE RESIN COMPOSITION AND MOLDED ARTICLE THEREOF | GENERAL ELECTRIC COMPAMY (US) | 2003-10-23 | — | — | WO | disclosed |