Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Potassium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 3/20 | 0.49 |
| ▸ | VCAM1 | P19320 | 2/20 | 0.47 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 3/20 | 0.43 |
| ▸ | CA2 | P00918 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.41 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4365595 | 0.96 | MMP2 (0.49) | MMP2VCAM1SRD5A2TDP1CA1 | |
| Potassium Ion SCHEMBL11586061 | 0.92 | VCAM1 (0.54) | MMP2VCAM1SRD5A2TDP1CA1 | |
| SCHEMBL5082265 | 0.91 | MMP2 (0.49) | MMP2VCAM1SRD5A2CA1CA2 | |
| SCHEMBL5082308 | 0.90 | MMP2 (0.48) | MMP2VCAM1SRD5A2CA1CA2 | |
| SCHEMBL250653 | 0.81 | MMP2 (0.51) | MMP2VCAM1SRD5A2TDP1CA1 | |
| SCHEMBL4365596 | 0.79 | MMP2 (0.50) | MMP2VCAM1SRD5A2TDP1CA1 | |
| SCHEMBL2572655 | 0.79 | MMP2 (0.50) | MMP2VCAM1SRD5A2TDP1CA1 | |
| SCHEMBL4365592 | 0.79 | MMP2 (0.50) | MMP2VCAM1SRD5A2TDP1CA1 | |
| Potassium Ion SCHEMBL2176793 | 0.78 | PTK2B (0.43) | SMN1; SMN2 | |
| Potassium Ion SCHEMBL29653831 | 0.76 | MCL1 (0.52) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8445141-B2 | Sulfonic acid group-containing polymer, method for producing the same, resin composition containing such sulfonic acid group-containing polymer, polymer electrolyte membrane, polymer electrolyte membrane/electrode assembly, and fuel cell | TOYO BOSEKI KABUSHIKI KAISHA (JP) | 2013-05-21 | — | — | US | disclosed |
| US-20090075147-A1 | Sulfonic acid group-containing polymer, method for producing the same, resin composition containing such sulfonic acid group-containing polymer, polymer electrolyte membrane, polymer electrolyte membrane/electrode assembly, and fuel cell | TOYO BOSEKI KABUSHIKI KAISHA (JP) | 2009-03-19 | — | — | US | disclosed |
| EP-1889863-A1 | SULFONIC ACID GROUP-CONTAINING POLYMER, METHOD FOR PRODUCING SAME, RESIN COMPOSITION CONTAINING SUCH SULFONIC ACID GROUP-CONTAINING POLYMER, POLYMER ELECTROLYTE MEMBRANE, POLYMER ELECTROLYTE MEMBRANE/ELECTRODE ASSEMBLY, AND FUEL CELL | Toyo Boseki Kabushiki Kasisha (JP) | 2008-02-20 | — | — | EP | disclosed |