Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VCP | P55072 | 1/20 | 0.35 |
| ▸ | APP | P05067 | 1/20 | 0.35 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.32 |
| ▸ | CES2 | O00748 | 1/20 | 0.31 |
| ▸ | CES1 | P23141 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CA3 | P07451 | 1/20 | 0.30 |
| ▸ | CA4 | P22748 | 1/20 | 0.30 |
| ▸ | CA6 | P23280 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL170296 | 0.84 | ALDH1A1 (0.46) | VCPAPPSRD5A2ALDH1A1TSHR | |
| SCHEMBL1127547 | 0.70 | ALDH1A1 (0.70) | SRD5A2ALDH1A1TSHRMEN1MAPT | |
| SCHEMBL5572176 | 0.69 | APP (0.67) | APPALDH1A1MEN1MAPTKMT2A | |
| SCHEMBL28417772 | 0.69 | APP (0.67) | APPALDH1A1MEN1MAPTKMT2A | |
| SCHEMBL14353960 | 0.69 | CES2 (0.43) | SRD5A2ALDH1A1TSHRHAO1CES2 | |
| SCHEMBL17416119 | 0.68 | ALDH1A1 (0.67) | SRD5A2ALDH1A1TSHRMEN1MAPT | |
| Benzene SCHEMBL10712312 | 0.66 | IDO1 (0.53) | ALDH1A1TSHRMAPTHAO1CA12 | |
| Benzenethiol SCHEMBL3155034 | 0.65 | TSHR (0.62) | SRD5A2ALDH1A1TSHRCES2CES1 | |
| SCHEMBL2925323 | 0.65 | ALDH1A1 (0.50) | VCPSRD5A2ALDH1A1MEN1KMT2A | |
| SCHEMBL15006706 | 0.65 | RAB9A (0.61) | SRD5A2ALDH1A1MEN1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080220283-A1 | SUBSTITUTED POLYACETYLENE, COMPLEX AND DEVICE STRUCTURE | CANON KABUSHIKI KAISHA (JP) | 2008-09-11 | — | — | US | disclosed |