SCHEMBL5083180

SCHEMBL5083180

COc1cc2ccn(C)c2cc1OC

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TUBB4A P04350 5/20 0.49
TUBB P07437 5/20 0.49
TUBA3C P0DPH7 5/20 0.49
TUBA1B P68363 5/20 0.49
TUBA4A P68366 5/20 0.49
TUBB4B P68371 5/20 0.49
TUBB3 Q13509 5/20 0.49
TUBB2A Q13885 5/20 0.49
TUBB8 Q3ZCM7 5/20 0.49
TUBA3E Q6PEY2 5/20 0.49
TUBA1A Q71U36 5/20 0.49
TUBA1C Q9BQE3 5/20 0.49
TUBB6 Q9BUF5 5/20 0.49
TUBB2B Q9BVA1 5/20 0.49
TUBB1 Q9H4B7 5/20 0.49
PRKCI P41743 1/20 0.47
CYP2A6 P11509 2/20 0.43
PIK3CB P42338 1/20 0.43
ALDH1A1 P00352 1/20 0.40
TFPI2 P48307 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19559075 0.86 TUBB4A (0.46) TUBB4ATUBBTUBA3CTUBA1BTUBA4A
SCHEMBL31457657 0.85 TUBB4A (0.44) TUBB4ATUBBTUBA3CTUBA1BTUBA4A
SCHEMBL31711098 0.85 TUBB4A (0.44) TUBB4ATUBBTUBA3CTUBA1BTUBA4A
SCHEMBL27440768 0.85 TUBB4A (0.44) TUBB4ATUBBTUBA3CTUBA1BTUBA4A
SCHEMBL3257747 0.85 TUBB4A (0.44) TUBB4ATUBBTUBA3CTUBA1BTUBA4A
SCHEMBL26654536 0.85 TUBB4A (0.44) TUBB4ATUBBTUBA3CTUBA1BTUBA4A
SCHEMBL15704611 0.85 TUBB4A (0.44) TUBB4ATUBBTUBA3CTUBA1BTUBA4A
SCHEMBL8053219 0.85 TUBB4A (0.48) TUBB4ATUBBTUBA3CTUBA1BTUBA4A
SCHEMBL22509234 0.85 PGK1 (0.48) TUBB4ATUBBTUBA3CTUBA1BTUBA4A
SCHEMBL12386831 0.82 LMNA (0.43) TUBB4ATUBBTUBA3CTUBA1BTUBA4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2582351-B1 HAIR DYEING PROCESS USING A COMPOSITION COMPRISING AT LEAST ONE INDOLE OR INDOLINE COMPOUND, A METAL SALT, HYDROGEN PEROXIDE AND A BASIFYING AGENT L'ORÉAL (FR) 2017-08-02 EP claimed
EP-0441689-B1 Process for enzymatic preparation of melanin pigment and its use in cosmetics OREAL (FR) 1994-12-14 EP claimed
US-5244497-A Polymerization of an indole compound L'OREAL (FR) 1993-09-14 US claimed
EP-0441689-A1 Process for enzymatic preparation of melanin pigment and its use in cosmetics L'OREAL (FR) 1991-08-14 EP claimed
US-11904014-B2 Immunostimulatory compositions Assistance Publique—Hopitaux de Paris (FR) 2024-02-20 US disclosed
CN-115772163-A Indole glycoside compounds and pyrrole glycoside compounds, and synthesis method and application thereof 中国科学院成都生物研究所 2023-03-10 CN disclosed
CN-108601826-B Immunostimulatory compositions 法国公立援助医院 2021-10-26 CN disclosed
EP-3380120-B1 IMMUNOSTIMULATORY COMPOSITIONS HOPITAUX PARIS ASSIST PUBLIQUE (FR) 2021-04-21 EP disclosed
US-20210060156-A1 IMMUNOSTIMULATORY COMPOSITIONS ASSISTANCE PUBLIQUE - HOPITAUX DE PARIS (FR) 2021-03-04 US disclosed
US-10857227-B2 Immunostimulatory compositions ASSISTANCE PUBLIQUE—HOSPITAUX DE PARIS (FR) 2020-12-08 US disclosed
US-10292921-B2 Hair dyeing process using a composition comprising at least one indol(in)e compound and a polycyclic aromatic compound containing at least ten carbon atoms L'OREAL (FR) 2019-05-21 US disclosed
US-20180333483-A1 IMMUNOSTIMULATORY COMPOSITIONS ASSISTANCE PUBLIQUE - HOPITAUX DE PARIS (FR) 2018-11-22 US disclosed
US-7314903-B2 Catalyst system for the polymerization of olefins BASELL POLYOLEFINE GMBH (DE) 2008-01-01 US disclosed
CN-1832970-A Catalyst system for olefin polymerization BASELL POLYOLEFINE GMBH (DE) 2006-09-13 CN disclosed
US-20060094840-A1 Catalyst system for the polymerization of olefins BASSELL POLLYOLEFINE GMBH (DE) 2006-05-04 US disclosed
EP-1611167-A2 CATALYST SYSTEM FOR THE POLYMERIZATION OF OLEFINS Basell Polyolefine GmbH (DE) 2006-01-04 EP disclosed
WO-2004005360-A2 CATALYST SYSTEM FOR THE POLYMERIZATION OF OLEFINS BASELL POLYOLEFINE GMBH (DE) 2004-01-15 WO disclosed
EP-0441689-B1 Process for enzymatic preparation of melanin pigment and its use in cosmetics OREAL (FR) 1994-12-14 EP disclosed
US-5244497-A Polymerization of an indole compound L'OREAL (FR) 1993-09-14 US disclosed
EP-0441689-A1 Process for enzymatic preparation of melanin pigment and its use in cosmetics L'OREAL (FR) 1991-08-14 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210060156-A1 IMMUNOSTIMULATORY COMPOSITIONS CD47, CD74, LY96 TUBB4A 3431/4885TUBB 3612/4885TUBA3C 3510/4885
US-10857227-B2 Immunostimulatory compositions CD47, CD74, LY96 TUBB4A 3431/4885TUBB 3612/4885TUBA3C 3510/4885
US-11904014-B2 Immunostimulatory compositions CD47, CD74, LY96 TUBB4A 3431/4885TUBB 3612/4885TUBA3C 3510/4885
US-20180333483-A1 IMMUNOSTIMULATORY COMPOSITIONS CD47, CD74, LY96 TUBB4A 3431/4885TUBB 3612/4885TUBA3C 3510/4885
US-10292921-B2 Hair dyeing process using a composition comprising at least one indol(in)e compound and a polycyclic aromatic compound containing at least ten carbon atoms KRT18, TYR, INCENP TUBB4A 56/4885TUBB 225/4885TUBA3C 725/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.