Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNN4 | O15554 | 1/20 | 0.42 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.39 |
| ▸ | HTR7 | P34969 | 2/20 | 0.38 |
| ▸ | AR | P10275 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.35 |
| ▸ | PDE5A | O76074 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | POLQ | O75417 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5081008 | 0.93 | KDM4E (0.40) | KCNN4ADRB2HTR7KDM4EL3MBTL1 | |
| SCHEMBL5083181 | 0.86 | KDM4E (0.41) | KCNN4ADRB2HTR7KDM4EPDE5A | |
| SCHEMBL5083191 | 0.86 | KDM4E (0.41) | KCNN4ADRB2HTR7KDM4EPDE5A | |
| SCHEMBL5087245 | 0.83 | CYP1A2 (0.35) | ADRB2HTR7KDM4EPDE5AL3MBTL1 | |
| SCHEMBL4721568 | 0.82 | PDE5A (0.41) | ADRB2KDM4EPDE5AALDH1A1LMNA | |
| SCHEMBL4723651 | 0.81 | CYP1A2 (0.48) | KDM4EPDE5ACYP1A2CYP2C19 | |
| SCHEMBL4723561 | 0.79 | ALDH1A1 (0.40) | KDM4EPDE5AALDH1A1MEN1KMT2A | |
| SCHEMBL5083208 | 0.78 | KCNN4 (0.31) | KCNN4KDM4EALDH1A1TSHR | |
| SCHEMBL478309 | 0.77 | HTR7 (0.56) | KCNN4ADRB2HTR7ARKDM4E | |
| SCHEMBL4724808 | 0.76 | APP (0.46) | KDM4EL3MBTL1ALDH1A1LMNACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7375081-B2 | Therapeutic combination of a pneumocandin derivative and an antifungal agent | ASTELLAS PHARMA INC. (JP) | 2008-05-20 | — | — | US | claimed |
| US-6875740-B1 | Combination of a cyclic hexapeptide with antifungal drugs for treatment of fungal pathogens | FUJISAWA PHARMACEUTICAL CO. LTD. (JP) | 2005-04-05 | — | — | US | claimed |