Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR1A | P37288 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.39 |
| ▸ | SIRT1 | Q96EB6 | 3/20 | 0.39 |
| ▸ | CFTR | P13569 | 1/20 | 0.38 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4725746 | 0.81 | TP53 (0.48) | AVPR1ANPSR1SIRT1CFTRGOPC | |
| SCHEMBL4726170 | 0.74 | CFTR (0.61) | NPSR1CFTRGOPCCYP3A4CYP1A2 | |
| SCHEMBL4728617 | 0.73 | CFTR (0.38) | CFTRGOPCACHEMAPTSMN1; SMN2 | |
| SCHEMBL4729629 | 0.73 | OPRM1 (0.53) | NPSR1CFTRGOPCCYP3A4CYP1A2 | |
| SCHEMBL11010153 | 0.69 | ALDH1A1 (0.45) | CYP3A4L3MBTL1ACHEMAPTSMN1; SMN2 | |
| SCHEMBL11831890 | 0.68 | SIGMAR1 (0.66) | AVPR1AACHE | |
| SCHEMBL11832778 | 0.65 | AVPR1A (0.50) | AVPR1ACYP3A4ACHEKDM4ECA1 | |
| SCHEMBL11731999 | 0.64 | CA1 (0.42) | AVPR1ANPSR1CYP3A4ACHEKDM4E | |
| SCHEMBL1820782 | 0.64 | CYP2D6 (0.48) | NPSR1CFTRGOPCCYP3A4HTT | |
| SCHEMBL8986118 | 0.63 | KDM4E (0.41) | NPSR1SIRT1CYP3A4ACHEMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080044390-A1 | Methods and compositions for the treatment of neurodegenerative disorders | CHDI, INCORPORATED | 2008-02-21 | — | — | US | disclosed |
| US-4505921-A | Sulfonylurea compounds and their use in treating diabetes | ADIR, S.A.R.L. (FR) | 1985-03-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080044390-A1 | Methods and compositions for the treatment of neurodegenerative disorders | HTT, SNCA, NLN | AVPR1A 4609/4885NPSR1 1396/4885SIRT1 399/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.