SCHEMBL5083263

SCHEMBL5083263

Cc1c(C)c(C(=O)c2ccc(O)cc2)c(C)c(C)c1O

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.58
MAPT P10636 3/20 0.58
HTT P42858 2/20 0.58
HPGD P15428 2/20 0.58
ESR1 P03372 2/20 0.58
ESR2 Q92731 2/20 0.58
PKM P14618 1/20 0.58
SMN1; SMN2 Q16637 1/20 0.52
SRD5A2 P31213 1/20 0.50
MAPK1 P28482 2/20 0.48
CYP2C19 P33261 1/20 0.46
EYA3 Q99504 1/20 0.46
MEN1 O00255 1/20 0.45
RAB9A P51151 1/20 0.45
KMT2A Q03164 1/20 0.45
CA1 P00915 4/20 0.44
CA2 P00918 4/20 0.44
CA12 O43570 3/20 0.44
CA7 P43166 3/20 0.44
CA9 Q16790 3/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3272242 0.77 LMNA (0.70) LMNAMAPTHTTHPGDESR1
SCHEMBL699850 0.75 LMNA (1.00) LMNAMAPTHTTHPGDESR1
SCHEMBL18423 0.75 LMNA (1.00) LMNAMAPTHTTHPGDESR1
SCHEMBL1101886 0.75 ALDH1A1 (0.80) LMNAMAPTHTTHPGDESR1
SCHEMBL8334138 0.75 ALDH1A1 (0.80) LMNAMAPTHTTHPGDESR1
SCHEMBL11017122 0.74 HTT (0.62) LMNAMAPTHTTHPGDESR1
SCHEMBL7929114 0.73 LMNA (0.94) LMNAMAPTHTTHPGDESR1
SCHEMBL29056089 0.73 LMNA (0.94) LMNAMAPTHTTHPGDESR1
Methane SCHEMBL6378712 0.73 LMNA (0.94) LMNAMAPTHTTHPGDESR1
Fluoride SCHEMBL16505425 0.73 LMNA (0.94) LMNAMAPTHTTHPGDESR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10081708-B2 Polycarbonate copolymer and preparation method therefor SAMYANG CORPORATION (KR) 2018-09-25 US claimed
CN-115443299-B Polysiloxane-polycarbonate copolymers utilizing hydroxyl-terminated polysiloxane mixtures and methods of making the same 株式会社三养社 2024-05-10 CN disclosed
CN-116813900-A Double-end hydroxyl low molecular weight polyphenyl ether and synthesis method thereof 北京赛福瑞技术服务有限公司 2023-09-29 CN disclosed
CN-115443299-A Polysiloxane-polycarbonate copolymers utilizing hydroxyl-terminated polysiloxane mixtures and methods of making the same 株式会社三养社 2022-12-06 CN disclosed
CN-112714783-B Thermoplastic resin composition 日本A&L株式会社 2022-11-11 CN disclosed
CN-110628013-B Bifunctional phosphorus-containing polyphenylene ether, and preparation method and application thereof 河北健馨生物科技有限公司 2022-06-24 CN disclosed
CN-114634695-A Resin composition and method for producing resin composition 索尼公司 2022-06-17 CN disclosed
CN-110506078-B Resin composition and method for producing resin composition 索尼公司 2022-03-29 CN disclosed
CN-113614178-A Thermoplastic resin composition and molded article 株式会社钟化 2021-11-05 CN disclosed
CN-110062792-B Polycarbonate resin composition having excellent heat resistance and flowability, and molded article comprising same 株式会社三养社 2021-06-29 CN disclosed
CN-108602958-B Polysiloxane-polycarbonate copolymer having improved transparency and flame retardancy and method for preparing the same 株式会社三养社 2021-02-05 CN disclosed
CN-108473670-B Polyester-polycarbonate copolymer and method for producing same 株式会社三养社 2020-06-23 CN disclosed
CN-110628013-A Bifunctional phosphorus-containing polyphenylene ether, and preparation method and application thereof 河北健馨生物科技有限公司 2019-12-31 CN disclosed
CN-105646791-A RUBBER GRAFT COPOLYMER, AND THERMOPLASTIC RESIN COMPOSITION CONTAINING RUBBER GRAFT COPOLYMER 株式会社钟化 2016-06-08 CN disclosed
CN-104704051-A Rubber graft copolymer and thermoplastic resin composition comprising the same KANEKA CORP 2015-06-10 CN disclosed
CN-104334523-A Ion-binding salt having reactive group and thermoplastic resin composition containing same NIPPON NYUKAZAI CO LTD 2015-02-04 CN disclosed
CN-104159977-A Thermoplastic resin composition NIPPON NYUKAZAI CO LTD 2014-11-19 CN disclosed
CN-103635534-A Thermoplastic resin composition and molded article comprising same TORAY INDUSTRIES 2014-03-12 CN disclosed
US-20080125527-A1 Flame-Retardant Resin Composition KANEKA CORPORATION (JP) 2008-05-29 US disclosed
US-20050004292-A1 Flame-retardant resin composition POLYPLASTICS CO., LTD. (JP) 2005-01-06 US disclosed