Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR4 | P61073 | 1/20 | 0.60 |
| ▸ | MAOB | P27338 | 1/20 | 0.50 |
| ▸ | GSK3B | P49841 | 1/20 | 0.49 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.47 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.47 |
| ▸ | MET | P08581 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | HSD17B13 | Q7Z5P4 | 1/20 | 0.46 |
| ▸ | AR | P10275 | 1/20 | 0.46 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.45 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.45 |
| ▸ | PPARG | P37231 | 3/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6543656 | 0.85 | THRB (0.55) | GSK3BEPHX2MEN1KMT2AAR | |
| SCHEMBL24154687 | 0.81 | MAOB (0.47) | CXCR4MAOBGSK3BEPHX2NR1H4 | |
| SCHEMBL3460904 | 0.81 | EPHX2 (0.57) | MAOBEPHX2NR1H4MEN1KMT2A | |
| SCHEMBL6782132 | 0.79 | EPHX2 (0.56) | MAOBEPHX2NR1H4PPARG | |
| SCHEMBL5083050 | 0.79 | L3MBTL1 (0.69) | CXCR4MEN1KMT2AL3MBTL1LMNA | |
| SCHEMBL13450242 | 0.79 | EPHX2 (0.62) | MAOBGSK3BEPHX2NR1H4MET | |
| SCHEMBL5643140 | 0.78 | EPHX2 (0.54) | MAOBGSK3BEPHX2NR1H4MEN1 | |
| SCHEMBL5645307 | 0.78 | EPHX2 (0.58) | MAOBEPHX2NR1H4P2RX7PPARG | |
| SCHEMBL5211695 | 0.77 | MEN1 (0.52) | MAOBGSK3BEPHX2NR1H4MET | |
| SCHEMBL27604226 | 0.77 | MAOB (0.50) | MAOBEPHX2NR1H4LMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080132505-A1 | Combination Of Cb2 Modulators And Pde4 Inhibitors For Use In Medicine | GLAXO GROUP LIMITED | 2008-06-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080132505-A1 | Combination Of Cb2 Modulators And Pde4 Inhibitors For Use In Medicine | CNR2, CNR1, PDE4A | CXCR4 72/4885MAOB 691/4885GSK3B 752/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.