Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 4/20 | 0.54 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.54 |
| ▸ | PPARG | P37231 | 5/20 | 0.48 |
| ▸ | MAOB | P27338 | 1/20 | 0.48 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | GSK3B | P49841 | 1/20 | 0.45 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | HSD17B13 | Q7Z5P4 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6782132 | 0.87 | EPHX2 (0.56) | EPHX2NR1H4PPARGMAOB | |
| SCHEMBL5642964 | 0.86 | LMNA (0.53) | EPHX2NR1H4 | |
| SCHEMBL5645307 | 0.85 | EPHX2 (0.58) | EPHX2NR1H4PPARGMAOB | |
| SCHEMBL3460904 | 0.85 | EPHX2 (0.57) | EPHX2NR1H4PPARGMAOBAKR1B1 | |
| SCHEMBL3962896 | 0.83 | LMNA (0.60) | EPHX2NR1H4PPARG | |
| SCHEMBL678099 | 0.81 | CA2 (0.70) | EPHX2NR1H4CA2KMT2A | |
| SCHEMBL5049108 | 0.79 | PPARG (0.59) | EPHX2NR1H4PPARGMAOB | |
| SCHEMBL5083302 | 0.78 | CXCR4 (0.60) | EPHX2NR1H4PPARGMAOBKLKB1 | |
| SCHEMBL5045508 | 0.78 | PPARG (0.58) | EPHX2NR1H4PPARGMAOB | |
| SCHEMBL5451331 | 0.77 | MAOB (0.44) | MAOBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7241759-B2 | Benzo[1,2,5]thiadiazole compounds | JANSSEN PHARMACEUTICA N.V. (BE) | 2007-07-10 | — | — | US | disclosed |