SCHEMBL5083331

SCHEMBL5083331

CCCC(OC(=O)c1ccccc1)C(CC(C)C)C(=O)OCC

nearest known ligand 0.43

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.43
KMT2A Q03164 4/20 0.43
MEN1 O00255 3/20 0.43
NPC1 O15118 2/20 0.43
SMN1; SMN2 Q16637 3/20 0.42
GAA P10253 3/20 0.42
POLB P06746 1/20 0.42
RAB9A P51151 1/20 0.42
KDM4E B2RXH2 1/20 0.41
TDP1 Q9NUW8 1/20 0.40
PRKCA P17252 1/20 0.40
TSHR P16473 2/20 0.40
MAPT P10636 3/20 0.39
ALDH1A1 P00352 1/20 0.39
TP53 P04637 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5079895 0.90 KMT2A (0.44) LMNAKMT2AMEN1NPC1SMN1; SMN2
SCHEMBL5085964 0.89 LMNA (0.47) LMNAKMT2AMEN1NPC1SMN1; SMN2
SCHEMBL5082885 0.88 LMNA (0.46) LMNAKMT2AMEN1NPC1SMN1; SMN2
SCHEMBL5082210 0.86 MEN1 (0.44) LMNAKMT2AMEN1NPC1SMN1; SMN2
SCHEMBL5085847 0.85 MMP8 (0.45) LMNAKMT2AMEN1NPC1SMN1; SMN2
SCHEMBL5082891 0.84 MEN1 (0.47) LMNAKMT2AMEN1NPC1SMN1; SMN2
SCHEMBL5085862 0.84 POLB (0.49) LMNAKMT2AMEN1NPC1SMN1; SMN2
SCHEMBL5085827 0.83 LMNA (0.46) LMNAKMT2AMEN1NPC1SMN1; SMN2
SCHEMBL5082902 0.82 LMNA (0.41) LMNAKMT2AMEN1NPC1SMN1; SMN2
SCHEMBL5082884 0.82 LMNA (0.45) LMNAKMT2AMEN1NPC1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1746110-B1 CATALYST COMPONENT FOR OLEFIN POLYMERIZATION REACTION AND CATALYST THEREOF CHINA PETROLEUM & CHEMICAL (CN) 2015-03-11 EP disclosed
US-7351778-B2 Catalyst component for olefin polymerization and catalyst comprising the same CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2008-04-01 US disclosed
EP-1746110-A1 CATALYST COMPONENT FOR OLEFIN POLYMERIZATION REACTION AND CATALYST THEREOF China Petroleum & Chemical Corporation (CN) 2007-01-24 EP disclosed
US-20060287446-A1 Catalyst component for olefin polymerization and catalyst comprising the same BEIJING RESEARCH INSTITUTE OF CHEMICAL INDUSTRY CHINA PETROLEUM & CHEMICAL COPORATION (CN) 2006-12-21 US disclosed