SCHEMBL5085847

SCHEMBL5085847

CCCC(OC(=O)c1ccccc1)C(Cc1ccccc1)C(=O)OCC

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MMP8 P22894 1/20 0.45
LMNA P02545 1/20 0.43
SMN1; SMN2 Q16637 4/20 0.43
KMT2A Q03164 3/20 0.43
NPC1 O15118 2/20 0.43
MEN1 O00255 2/20 0.43
POLB P06746 1/20 0.42
EPHX2 P34913 1/20 0.41
PPARG P37231 1/20 0.41
SLC6A2 P23975 1/20 0.41
SLC6A3 Q01959 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
PRKCA P17252 1/20 0.40
GAA P10253 2/20 0.39
RAB9A P51151 2/20 0.39
TP53 P04637 2/20 0.39
TSHR P16473 1/20 0.39
ALDH1A1 P00352 1/20 0.39
MAPT P10636 2/20 0.39
NAMPT P43490 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5082107 0.90 MMP8 (0.47) MMP8LMNASMN1; SMN2KMT2ANPC1
SCHEMBL5085964 0.89 LMNA (0.47) LMNASMN1; SMN2KMT2ANPC1MEN1
SCHEMBL5186628 0.88 SLC1A3 (0.45) LMNAKMT2AMEN1PPARGSLC6A2
SCHEMBL5082885 0.88 LMNA (0.46) LMNASMN1; SMN2KMT2ANPC1MEN1
SCHEMBL5082210 0.86 MEN1 (0.44) LMNASMN1; SMN2KMT2ANPC1MEN1
SCHEMBL5083331 0.85 LMNA (0.43) LMNASMN1; SMN2KMT2ANPC1MEN1
SCHEMBL5082842 0.83 MMP8 (0.48) MMP8LMNASMN1; SMN2KMT2ANPC1
SCHEMBL5085827 0.83 LMNA (0.46) LMNASMN1; SMN2KMT2ANPC1MEN1
SCHEMBL5082902 0.82 LMNA (0.41) LMNASMN1; SMN2KMT2ANPC1MEN1
SCHEMBL5085862 0.81 POLB (0.49) LMNASMN1; SMN2KMT2ANPC1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1746110-B1 CATALYST COMPONENT FOR OLEFIN POLYMERIZATION REACTION AND CATALYST THEREOF CHINA PETROLEUM & CHEMICAL (CN) 2015-03-11 EP disclosed
CN-101759816-A Method for preparing a catalyst component for olefinic polymerization, and a catalyst component thereof CHINA PETROLEUM & CHEMICAL 2010-06-30 CN disclosed
CN-100429242-C Catalyst components for olefinic polyreaction and catalyst thereof CHINA PETROLEUM & CHEMICAL (CN) 2008-10-29 CN disclosed
CN-100429243-C Method for preparing catalyst constituent for olefinic polymerization CHINA PETROCHEMICAL CO LTD (CN) 2008-10-29 CN disclosed
US-7351778-B2 Catalyst component for olefin polymerization and catalyst comprising the same CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2008-04-01 US disclosed
CN-100348624-C Catalyst components for olefinic polyreaction and catalyst thereof CHINA PETROLEUM & CHEMICAL (CN) 2007-11-14 CN disclosed
EP-1746110-A1 CATALYST COMPONENT FOR OLEFIN POLYMERIZATION REACTION AND CATALYST THEREOF China Petroleum & Chemical Corporation (CN) 2007-01-24 EP disclosed
CN-1891722-A Method for preparing catalyst constituent for olefinic polymerization CHINA PETROCHEMICAL CO LTD (CN) 2007-01-10 CN disclosed
US-20060287446-A1 Catalyst component for olefin polymerization and catalyst comprising the same BEIJING RESEARCH INSTITUTE OF CHEMICAL INDUSTRY CHINA PETROLEUM & CHEMICAL COPORATION (CN) 2006-12-21 US disclosed
CN-1282670-C Catalyst components for olefinic polyreaction and catalyst thereof CHINA PETROLEUM & CHEMICAL (CN) 2006-11-01 CN disclosed
CN-1803862-A Catalyst components for olefinic polyreaction and catalyst thereof CHINA PETROLEUM & CHEMICAL (CN) 2006-07-19 CN disclosed
CN-1803863-A Catalyst components for olefinic polyreaction and catalyst thereof CHINA PETROLEUM & CHEMICAL (CN) 2006-07-19 CN disclosed
CN-1690090-A Catalyst components for olefinic polyreaction and catalyst thereof SINOPEC CORP (CN) 2005-11-02 CN disclosed