Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL399507 | 0.98 | MRGPRX4 (0.32) | MRGPRX4ALDH1A1 | |
| Bromide SCHEMBL5079330 | 0.92 | ALDH1A1 (0.31) | MRGPRX4ALDH1A1 | |
| Hydrochloric Acid SCHEMBL5080396 | 0.91 | POLB (0.30) | MRGPRX4 | |
| Hydrochloric Acid SCHEMBL5077685 | 0.89 | ALDH1A1 (0.31) | MRGPRX4ALDH1A1 | |
| Hydrochloric Acid SCHEMBL5083581 | 0.89 | — | — | |
| Hydrochloric Acid SCHEMBL19127395 | 0.89 | MRGPRX4 (0.31) | MRGPRX4 | |
| Hydrochloric Acid SCHEMBL4293920 | 0.89 | — | — | |
| Hydrochloric Acid SCHEMBL8511528 | 0.88 | OPRD1 (0.31) | ALDH1A1 | |
| Hydrochloric Acid SCHEMBL19127661 | 0.88 | — | — | |
| Hydrochloric Acid SCHEMBL19126944 | 0.88 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7393965-B2 | Crosslinked metallocene compound for olefin polymerization and method of polymerizing olefin with the same | MITSUI CHEMICALS, INC. (JP) | 2008-07-01 | — | — | US | disclosed |
| US-20060161013-A1 | Crosslinked metallocene compound for olefin polymerization and method of polymerizing olefin with the same | MITSUI CHEMICALS, INC. (JP) | 2006-07-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060161013-A1 | Crosslinked metallocene compound for olefin polymerization and method of polymerizing olefin with the same | PCNA, MACF1, PIN1 | MRGPRX4 4159/4885ALDH1A1 2154/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.