Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5083392 | 0.98 | NPC1 (0.32) | NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL218253 | 0.92 | NPC1 (0.35) | NPC1RAB9ASRD5A2 | |
| Fluoride Ion SCHEMBL1130666 | 0.90 | NPC1 (0.35) | NPC1RAB9ASRD5A2 | |
| Hydrochloric Acid SCHEMBL5083621 | 0.89 | NPC1 (0.32) | NPC1RAB9ASRD5A2 | |
| Hydrochloric Acid SCHEMBL7915236 | 0.88 | NPC1 (0.33) | NPC1RAB9ASRD5A2 | |
| Hydrochloric Acid SCHEMBL5077688 | 0.86 | NPC1 (0.33) | NPC1RAB9ASRD5A2 | |
| Hydrochloric Acid SCHEMBL5081155 | 0.86 | PNMT (0.31) | NPC1RAB9ASRD5A2 | |
| Hydrochloric Acid SCHEMBL5079498 | 0.85 | KCNK9 (0.30) | KCNK9 | |
| Hydrochloric Acid SCHEMBL2115993 | 0.84 | NPC1 (0.32) | NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL5081189 | 0.84 | NPC1 (0.32) | NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7393965-B2 | Crosslinked metallocene compound for olefin polymerization and method of polymerizing olefin with the same | MITSUI CHEMICALS, INC. (JP) | 2008-07-01 | — | — | US | disclosed |
| US-20060161013-A1 | Crosslinked metallocene compound for olefin polymerization and method of polymerizing olefin with the same | MITSUI CHEMICALS, INC. (JP) | 2006-07-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060161013-A1 | Crosslinked metallocene compound for olefin polymerization and method of polymerizing olefin with the same | PCNA, MACF1, PIN1 | KCNK9 3441/4885NPC1 3370/4885RAB9A 4464/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.