SCHEMBL5084352

SCHEMBL5084352

CC1=C([Zr](Oc2ccccc2C(F)(F)F)(Oc2ccccc2C(F)(F)F)C2=CC=CC2)C(C)c2ccccc21

nearest known ligand 0.32

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
HSD11B1 P28845 1/20 0.32
SLC6A2 P23975 3/20 0.31
SLC6A4 P31645 3/20 0.31
SLC6A3 Q01959 2/20 0.31
HTR1A P08908 1/20 0.31
CYP2D6 P10635 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5085002 0.81 ADRA2A (0.35) HSD11B1SLC6A2SLC6A4SLC6A3HTR1A
SCHEMBL5081513 0.70 ALDH1A1 (0.38) CYP2D6
SCHEMBL5501754 0.69 SLC6A4 (0.33) SLC6A4
SCHEMBL5084334 0.69
SCHEMBL5084348 0.68 HSD11B1 (0.32) HSD11B1
SCHEMBL5087341 0.68 MRGPRX4 (0.36) SLC6A2SLC6A4
SCHEMBL5084993 0.68 TSHR (0.34) SLC6A2SLC6A4SLC6A3CYP2D6
SCHEMBL5081557 0.67 HRH1 (0.36)
SCHEMBL5498575 0.67 SYK (0.42) SLC6A4
SCHEMBL5499647 0.66 ADRA2A (0.35)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7345119-B2 Olefin polymerization catalyst and olefin polymerization method using the same MARUZEN PETROCHEMICAL COMPANY, LIMITED (JP) 2008-03-18 US disclosed
US-20050215736-A1 Olefin polymerization catalyst and olefin polymerization method using the same MARUZEN PETROCHEMICAL COMPANY, LIMITED (JP) 2005-09-29 US disclosed
EP-1541598-A1 Olefin polymerization catalyst and olefin polymerization method using the same MARUZEN PETROCHEMICAL CO., LTD. (JP) 2005-06-15 EP disclosed