SCHEMBL5084348

SCHEMBL5084348

CC1=CC(C)([Zr](Oc2ccccc2C(F)(F)F)(Oc2ccccc2C(F)(F)F)C2=CC=CC2)c2ccccc21

nearest known ligand 0.33

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
HSD11B1 P28845 1/20 0.32
PDK2 Q15119 1/20 0.30
TDP1 Q9NUW8 2/20 0.30
L3MBTL1 Q9Y468 2/20 0.30
ATM Q13315 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5085002 0.74 ADRA2A (0.35) HSD11B1
SCHEMBL5084352 0.68 HSD11B1 (0.32) HSD11B1
SCHEMBL5081513 0.62 ALDH1A1 (0.38) TDP1ATM
SCHEMBL5501754 0.61 SLC6A4 (0.33)
Hydrochloric Acid SCHEMBL3672116 0.61 ALDH1A1 (0.33) TDP1L3MBTL1
SCHEMBL5084334 0.61
SCHEMBL5083556 0.61 HSD11B1 (0.34) HSD11B1
SCHEMBL5087341 0.61 MRGPRX4 (0.36)
SCHEMBL5084993 0.60 TSHR (0.34) TDP1
SCHEMBL5087204 0.59 ADRA2A (0.33) HSD11B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7345119-B2 Olefin polymerization catalyst and olefin polymerization method using the same MARUZEN PETROCHEMICAL COMPANY, LIMITED (JP) 2008-03-18 US disclosed
US-20050215736-A1 Olefin polymerization catalyst and olefin polymerization method using the same MARUZEN PETROCHEMICAL COMPANY, LIMITED (JP) 2005-09-29 US disclosed
EP-1541598-A1 Olefin polymerization catalyst and olefin polymerization method using the same MARUZEN PETROCHEMICAL CO., LTD. (JP) 2005-06-15 EP disclosed