Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL2720720 | 0.68 | — | — | |
| Hydrochloric Acid SCHEMBL7769237 | 0.66 | — | — | |
| Hydrochloric Acid SCHEMBL27552036 | 0.64 | — | — | |
| SCHEMBL7188788 | 0.63 | CYP3A4 (0.44) | — | |
| SCHEMBL28394789 | 0.62 | ADRA2A (0.33) | — | |
| SCHEMBL12802395 | 0.62 | GABRA1 (0.42) | — | |
| SCHEMBL12802709 | 0.62 | GABRA1 (0.40) | — | |
| SCHEMBL88563 | 0.59 | LIPG (0.50) | — | |
| Biphenyl SCHEMBL27504184 | 0.59 | NR1H2 (0.35) | — | |
| Hydrochloric Acid SCHEMBL6294312 | 0.59 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1943307-A1 | MULTIMODAL POLYETHYLENE COMPOSITIONS AND PIPES MADE FROM THE SAME MULTIMODAL POLYETHYLENE COMPOSITION | Chevron Phillips Chemical Company LP (US) | 2008-07-16 | — | — | EP | disclosed |
| WO-2007055978-A1 | MULTIMODAL POLYETHYLENE COMPOSITIONS AND PIPES MADE FROM THE SAME MULTIMODAL POLYETHYLENE COMPOSITION | CHEVRON PHILLIPS CHEMICAL COMPANY, LP (US) | 2007-05-18 | — | — | WO | disclosed |