Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 1/20 | 0.40 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | TP53 | P04637 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.44 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.42 |
| ▸ | CNR2 | P34972 | 2/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.40 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5293784 | 0.98 | DNM1 (0.58) | DNM1MEN1KMT2ATP53SMN1; SMN2 | |
| Iodide SCHEMBL5091862 | 0.96 | DNM1 (0.56) | DNM1MEN1KMT2ATP53SMN1; SMN2 | |
| Bromide SCHEMBL635745 | 0.96 | DNM1 (0.59) | DNM1MEN1KMT2ATP53SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL635378 | 0.96 | MEN1 (0.59) | DNM1MEN1KMT2ATP53SMN1; SMN2 | |
| Iodide SCHEMBL239944 | 0.96 | DNM1 (0.56) | DNM1MEN1KMT2ATP53SMN1; SMN2 | |
| Iodide SCHEMBL5085453 | 0.94 | DNM1 (0.65) | DNM1MEN1KMT2ATP53SMN1; SMN2 | |
| Hydrogen Sulfide SCHEMBL5998244 | 0.94 | DNM1 (0.58) | DNM1MEN1KMT2ATP53SMN1; SMN2 | |
| SCHEMBL81000 | 0.94 | DNM1 (0.58) | DNM1MEN1KMT2ATP53SMN1; SMN2 | |
| SCHEMBL8569001 | 0.94 | DNM1 (0.58) | DNM1MEN1KMT2ATP53SMN1; SMN2 | |
| Iodide SCHEMBL5086633 | 0.92 | DNM1 (0.68) | DNM1MEN1KMT2ATP53SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080214386-A1 | Stability; easily separated from solution; surface treatment of catalyst with Group seven compound; reacting epoxide with carbon dioxide | NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) | 2008-09-04 | — | — | US | disclosed |