Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.59 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.59 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 4/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | F2 | P00734 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5085480 | 0.91 | PPARG (0.71) | PPARGTDP1KMT2ASLC6A2SLC6A3 | |
| Ethyl Benzoate SCHEMBL29016078 | 0.84 | SMN1; SMN2 (0.56) | TDP1KMT2ASLC6A2SLC6A3SMN1; SMN2 | |
| SCHEMBL6243415 | 0.84 | PPARG (0.63) | PPARGTDP1KMT2ASLC6A2SLC6A3 | |
| SCHEMBL28982407 | 0.82 | PPARG (0.61) | PPARGTDP1KMT2ASLC6A2SLC6A3 | |
| SCHEMBL6245188 | 0.82 | PPARG (0.61) | PPARGTDP1KMT2ASLC6A2SLC6A3 | |
| SCHEMBL4445832 | 0.82 | PPARG (0.61) | PPARGTDP1KMT2ASLC6A2SLC6A3 | |
| SCHEMBL27841681 | 0.81 | PPARG (0.60) | PPARGTDP1KMT2ASLC6A2SLC6A3 | |
| SCHEMBL4577944 | 0.81 | PPARG (0.65) | PPARGTDP1KMT2ASLC6A2SLC6A3 | |
| SCHEMBL336833 | 0.80 | PPARG (0.63) | PPARGTDP1KMT2ASLC6A2SLC6A3 | |
| SCHEMBL4070163 | 0.79 | LMNA (0.70) | PPARGTDP1KMT2ASLC6A2SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105287472-B | Antibacterial agent is used to treat the purposes of epithelial-related disease condition | 西格纳姆生物科学公司 | 2019-04-12 | — | — | CN | disclosed |
| CN-105287472-A | Antibacterial agent for treating the related state of illness about epithelium | SIGNUM BIOSCIENCES INC | 2016-02-03 | — | — | CN | disclosed |
| CN-102655745-B | Use of antibacterial agents for treating epithelial-related conditions | SIGNUM BIOSCIENCES, INC. (US) | 2016-01-06 | — | — | CN | disclosed |
| CN-102203067-B | Hedgehog pathway modulators | IRM LLC | 2014-01-15 | — | — | CN | disclosed |
| US-20130190502-A1 | ACYLATION REACTION OF HYDROXYL GROUP | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2013-07-25 | — | — | US | disclosed |
| US-8431709-B2 | Acylation reaction of hydroxyl group | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2013-04-30 | — | — | US | disclosed |
| US-20100249422-A1 | ACYLATION REACTION OF HYDROXYL GROUP | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2010-09-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130190502-A1 | ACYLATION REACTION OF HYDROXYL GROUP | ADH5, ADH1A, ACADM | PPARG 350/4885TDP1 4433/4885KMT2A 581/4885 |
| US-20100249422-A1 | ACYLATION REACTION OF HYDROXYL GROUP | ADH5, ADH1A, ACADM | PPARG 350/4885TDP1 4433/4885KMT2A 581/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.