SCHEMBL5086079

SCHEMBL5086079

C=C(CCCNCCO)C(=O)O

nearest known ligand 0.39

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 6/20 0.37
SMN1; SMN2 Q16637 4/20 0.36
HTT P42858 2/20 0.36
NPC1 O15118 1/20 0.36
RAB9A P51151 1/20 0.36
LMNA P02545 3/20 0.34
ALDH1A1 P00352 3/20 0.34
POLB P06746 2/20 0.34
MEN1 O00255 1/20 0.34
KMT2A Q03164 1/20 0.34
TBXAS1 P24557 2/20 0.33
ALOX15 P16050 1/20 0.33
HSD17B10 Q99714 1/20 0.33
TET2 Q6N021 2/20 0.32
PAOX Q6QHF9 1/20 0.32
CAMK2A Q9UQM7 1/20 0.31
FNTA P49354 1/20 0.31
FNTB P49356 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL819365 0.92 CAMK2A (0.36) KDM4ETBXAS1ALOX15HSD17B10TET2
SCHEMBL5086166 0.87 ALOX15 (0.35) KDM4ESMN1; SMN2HTTNPC1RAB9A
SCHEMBL7779000 0.85 ALOX15 (0.34) TBXAS1ALOX15HSD17B10TET2
SCHEMBL3140244 0.85 LMNA (0.42) LMNAALDH1A1KMT2AALOX15HSD17B10
SCHEMBL2495440 0.83 CA12 (0.44) KDM4ELMNAALDH1A1MEN1KMT2A
SCHEMBL246135 0.82 ALOX15 (0.45) KDM4ESMN1; SMN2ALDH1A1MEN1KMT2A
SCHEMBL636292 0.82 PAOX (0.47) ALDH1A1TBXAS1ALOX15TET2PAOX
SCHEMBL4276362 0.80 ALDH1A1 (0.50) ALDH1A1ALOX15PAOXFNTAFNTB
SCHEMBL303227 0.79 CYP2C19 (0.42) MEN1KMT2ATBXAS1ALOX15HSD17B10
SCHEMBL4275962 0.79 TSHR (0.48) ALDH1A1MEN1KMT2AALOX15HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080207797-A1 Anti-Fogging Coating Solution and Anti-Fogging Article SDC TECHNOLOGIES-ASIA LTD. (JP) 2008-08-28 US disclosed
US-4405679-A ADDITION POLYMER, POLYSILOXANE NIPPON SHEET GLASS CO. LTD. (JP) 1983-09-20 US disclosed