Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 4/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 5/20 | 0.36 |
| ▸ | ESR1 | P03372 | 3/20 | 0.35 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.35 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5091331 | 0.99 | SLC6A4 (0.42) | SLC6A4SLC6A3SLC6A2OPRM1ESR2 | |
| SCHEMBL8028845 | 0.85 | SLC6A2 (0.52) | SLC6A4SLC6A3SLC6A2OPRM1ESR2 | |
| SCHEMBL902452 | 0.85 | SLC6A2 (0.52) | SLC6A4SLC6A3SLC6A2OPRM1ESR2 | |
| SCHEMBL8028820 | 0.85 | SLC6A2 (0.52) | SLC6A4SLC6A3SLC6A2OPRM1ESR2 | |
| SCHEMBL4948718 | 0.72 | SLC6A2 (0.72) | SLC6A4SLC6A3SLC6A2OPRM1LMNA | |
| SCHEMBL4627006 | 0.72 | OPRM1 (0.39) | SLC6A4SLC6A3SLC6A2OPRM1LMNA | |
| Hydrochloric Acid SCHEMBL5512452 | 0.71 | SLC6A2 (0.72) | SLC6A4SLC6A3SLC6A2OPRM1LMNA | |
| SCHEMBL4632472 | 0.71 | CHRNB2 (0.43) | SLC6A4SLC6A3SLC6A2KMT2ALMNA | |
| SCHEMBL902225 | 0.70 | SLC6A2 (0.56) | SLC6A4SLC6A3SLC6A2OPRM1KMT2A | |
| SCHEMBL4967524 | 0.70 | SLC6A2 (0.56) | SLC6A4SLC6A3SLC6A2OPRM1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1904434-A2 | HIGHLY SELECTIVE SEROTONIN AND NOREPINEPHRINE DUAL REUPTAKE INHIBITOR AND USE THEREOF | Wyeth a Corporation of the State of Delaware (US) | 2008-04-02 | — | — | EP | disclosed |
| WO-2007011594-A2 | HIGHLY SELECTIVE SEROTONIN AND NOREPINEPHRINE DUAL REUPTAKE INHIBITOR AND USE THEREOF | WYETH (US) | 2007-01-25 | — | — | WO | disclosed |