Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A2 | P31213 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | PNMT | P11086 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | DRD4 | P21917 | 1/20 | 0.31 |
| ▸ | DRD3 | P35462 | 1/20 | 0.31 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.30 |
| ▸ | PGR | P06401 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL617844 | 0.86 | NPC1 (0.37) | SRD5A2NPC1RAB9APNMTDRD2 | |
| SCHEMBL6522771 | 0.84 | NPC1 (0.37) | SRD5A2NPC1RAB9APNMTDRD2 | |
| Fluoride Ion SCHEMBL3469916 | 0.84 | NPC1 (0.37) | SRD5A2NPC1RAB9APNMTDRD2 | |
| Hydrochloric Acid SCHEMBL8166519 | 0.83 | — | — | |
| Hydrochloric Acid SCHEMBL7930878 | 0.83 | SRD5A2 (0.32) | SRD5A2 | |
| Hydrochloric Acid SCHEMBL9083565 | 0.81 | PNMT (0.34) | SRD5A2NPC1RAB9APNMTDRD2 | |
| Hydrochloric Acid SCHEMBL7938803 | 0.81 | SRD5A2 (0.33) | SRD5A2 | |
| Hydrochloric Acid SCHEMBL7937398 | 0.81 | — | — | |
| Hydrochloric Acid SCHEMBL618232 | 0.79 | PNMT (0.33) | NPC1RAB9APNMTDRD2DRD4 | |
| Hydrochloric Acid SCHEMBL944866 | 0.79 | PNMT (0.33) | NPC1RAB9APNMTDRD2DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 51 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2721078-A1 | MULTI-COMPONENT CATALYST SYSTEMS FOR THE PRODUCTION OF REACTOR BLENDS OF POLYPROPYLENE | Fina Technology, Inc. (US) | 2014-04-23 | — | — | EP | claimed |
| WO-2013176685-A1 | MULTI-COMPONENT CATALYST SYSTEMS FOR THE PRODUCTION OF REACTOR BLENDS OF POLYPROPYLENE | FINA TECHNOLOGY, INC. (US) | 2013-11-28 | — | — | WO | claimed |
| EP-0849286-B1 | Improved polymer yield from supported metallocene catalysts | FINA TECHNOLOGY (US) | 2003-05-21 | — | — | EP | claimed |
| US-5968864-A | METALLOCENE CATALYSTS ON ALUMOXANES ON SILICA | FINA TECHNOLOGY, INC. (US) | 1999-10-19 | — | — | US | claimed |
| US-5847059-A | Catalyst yield from supported metallocene catalysts | FINA TECHNOLOGY, INC. (US) | 1998-12-08 | — | — | US | claimed |
| EP-0874003-A1 | Process for co-polymerization of olefins | FINA TECHNOLOGY, INC. (US) | 1998-10-28 | — | — | EP | claimed |
| US-5789502-A | METALLOCENE CATALYST | FINA TECHNOLOGY, INC. (US) | 1998-08-04 | — | — | US | claimed |
| EP-0849286-A1 | Improved polymer yield from supported metallocene catalysts | FINA TECHNOLOGY, INC. (US) | 1998-06-24 | — | — | EP | claimed |
| EP-2721078-A1 | MULTI-COMPONENT CATALYST SYSTEMS FOR THE PRODUCTION OF REACTOR BLENDS OF POLYPROPYLENE | Fina Technology, Inc. (US) | 2014-04-23 | — | — | EP | disclosed |
| WO-2013176685-A1 | MULTI-COMPONENT CATALYST SYSTEMS FOR THE PRODUCTION OF REACTOR BLENDS OF POLYPROPYLENE | FINA TECHNOLOGY, INC. (US) | 2013-11-28 | — | — | WO | disclosed |
| US-7368411-B2 | Supported metallocene catalysts and their use in producing stereospecific polymers | FINA TECHNOLOGY, INC (US) | 2008-05-06 | — | — | US | disclosed |
| US-20070135598-A1 | Supported metallocene catalysts and their use in producing stereospecific polymers | FINA TECHNOLOGY, INC. | 2007-06-14 | — | — | US | disclosed |
| US-7211536-B2 | Supported metallocene catalysts and their use in producing stereospecific polymers | FINA TECHNOLOGY, INC. (US) | 2007-05-01 | — | — | US | disclosed |
| WO-2006047396-A2 | SUPPORTED METALLOCENE CATALYSTS AND THEIR USE IN PRODUCING STEREOSPECIFIC POLYMERS | FINA TECHNOLOGY, INC. (US) | 2006-05-04 | — | — | WO | disclosed |
| US-5326824-A | Syndiotactic propylene copolymer, method for preparing same, and its use | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1994-07-05 | — | — | US | disclosed |
| EP-0553491-A1 | Catalyst for polymerization of olefins and process for production of olefin polymers | TOSOH CORPORATION (JP) | 1993-08-04 | — | — | EP | disclosed |
| US-5219968-A | PROPYLENE COPOLYMER | MITSUI TOATSU CHEMICALS, INC. (JP) | 1993-06-15 | — | — | US | disclosed |
| EP-0476148-A1 | PROPYLENE COPOLYMER | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1992-03-25 | — | — | EP | disclosed |
| EP-0459264-A2 | Method for preparing syndiotactic poly (alpha-olefin) | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1991-12-04 | — | — | EP | disclosed |
| EP-0457291-A2 | Syndiotactic propylene copolymer, method for preparing same, and its use | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1991-11-21 | — | — | EP | disclosed |