Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 known ✓ | P23975 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | PNMT | P11086 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | DRD4 | P21917 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.32 |
| ▸ | PGR | P06401 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6522771 | 0.97 | NPC1 (0.37) | NPC1RAB9APNMTDRD2DRD4 | |
| Fluoride Ion SCHEMBL3469916 | 0.97 | NPC1 (0.37) | NPC1RAB9APNMTDRD2DRD4 | |
| Hydrochloric Acid SCHEMBL5086526 | 0.86 | SRD5A2 (0.35) | NPC1RAB9APNMTDRD2DRD4 | |
| Hydrochloric Acid SCHEMBL9083565 | 0.84 | PNMT (0.34) | NPC1RAB9APNMTDRD2DRD4 | |
| Hydrochloric Acid SCHEMBL7766788 | 0.82 | NPC1 (0.32) | NPC1RAB9AALDH1A1 | |
| Hydrochloric Acid SCHEMBL8160701 | 0.82 | — | — | |
| Hydrochloric Acid SCHEMBL944866 | 0.82 | PNMT (0.33) | NPC1RAB9APNMTDRD2DRD4 | |
| Hydrochloric Acid SCHEMBL618232 | 0.82 | PNMT (0.33) | NPC1RAB9APNMTDRD2DRD4 | |
| Hydrochloric Acid SCHEMBL3894866 | 0.82 | PNMT (0.33) | NPC1RAB9APNMTDRD2DRD4 | |
| Hydrochloric Acid SCHEMBL7774360 | 0.80 | NPC1 (0.30) | NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 358 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0678530-B1 | Process for production of cyclic olefin copolymers and copolymers produced by said process | MITSUI CHEMICALS INC (JP) | 2001-07-25 | — | — | EP | claimed |
| US-6225251-B1 | Catalyst efficiency for supported metallocene catalyst | FINA TECHNOLOGY, INC. | 2001-05-01 | — | — | US | claimed |
| US-6201081-B1 | CATALYTIC OLEFIN POLYMERIZATION WITH CYCLOPENTADIENYL METAL CATALYST WITH SILICA AND ALUMOXANE IN SOLVENT | FINE TECHNOLOGY, INC. | 2001-03-13 | — | — | US | claimed |
| EP-0874003-A1 | Process for co-polymerization of olefins | FINA TECHNOLOGY, INC. (US) | 1998-10-28 | — | — | EP | claimed |
| US-5789502-A | METALLOCENE CATALYST | FINA TECHNOLOGY, INC. (US) | 1998-08-04 | — | — | US | claimed |
| US-5559199-A | MOLECULAR WEIGHT CONTROL | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1996-09-24 | — | — | US | claimed |
| EP-0678530-A1 | Process for production of cyclic olefin copolymers and copolymers produced by said process | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1995-10-25 | — | — | EP | claimed |
| US-5407882-A | Olefin polymerization catalyst and olefin polymerization process | TOSOH CORPORATION (JP) | 1995-04-18 | — | — | US | claimed |
| US-10870715-B2 | Solid polyaluminoxane composition, olefin polymerization catalyst, olefin polymer production method and solid polyaluminoxane composition production method | MITSUI CHEMICALS, INC. (JP) | 2020-12-22 | — | — | US | disclosed |
| EP-3312200-B1 | SOLID POLYALUMINOXANE COMPOSITION, OLEFIN POLYMERIZATION CATALYST, OLEFIN POLYMER PRODUCTION METHOD AND SOLID POLYALUMINOXANE COMPOSITION PRODUCTION METHOD | MITSUI CHEMICALS INC (JP) | 2019-06-19 | — | — | EP | disclosed |
| US-10150823-B2 | Solid polyaluminoxane composition, olefin polymerization catalyst, olefin polymer production method and solid polyaluminoxane composition production method | MITSUI CHEMICALS, INC. (JP) | 2018-12-11 | — | — | US | disclosed |
| EP-3312200-A1 | SOLID POLYALUMINOXANE COMPOSITION, OLEFIN POLYMERIZATION CATALYST, OLEFIN POLYMER PRODUCTION METHOD AND SOLID POLYALUMINOXANE COMPOSITION PRODUCTION METHOD | Mitsui Chemicals, Inc. (JP) | 2018-04-25 | — | — | EP | disclosed |
| EP-2955187-B1 | SOLID POLYALUMINOXANE COMPOSITION, CATALYST FOR OLEFIN POLYMERIZATION AND METHOD FOR PRODUCING OLEFIN POLYMER | MITSUI CHEMICALS INC (JP) | 2018-01-31 | — | — | EP | disclosed |
| US-20170240664-A1 | SOLID POLYALUMINOXANE COMPOSITION, OLEFIN POLYMERIZATION CATALYST, OLEFIN POLYMER PRODUCTION METHOD AND SOLID POLYALUMINOXANE COMPOSITION PRODUCTION METHOD | MITSUI CHEMICALS, INC. (JP) | 2017-08-24 | — | — | US | disclosed |
| EP-0452920-A2 | Process for the preparation of an ethylene copolymer and an olefin polymer, and catalysts for olefin polymerization | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1991-10-23 | — | — | EP | disclosed |
| EP-0447035-A2 | Method for the preparation of ethylene polymer compositions | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1991-09-18 | — | — | EP | disclosed |
| EP-0442725-A2 | Olefin polymerization solid catalysts and process for the polymerization of olefins | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1991-08-21 | — | — | EP | disclosed |
| EP-0439964-A2 | Olefin polymerization catalyst and process for the polymerization of olefins | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1991-08-07 | — | — | EP | disclosed |
| US-5036034-A | A syndiospecific polymerization catalyst having non-bilateral symmetry to obtain an amorphous poly-alpha-olefin | FINA TECHNOLOGY, INC. (US) | 1991-07-30 | — | — | US | disclosed |
| EP-0436399-A2 | Olefin polymerization catalyst and process for the polymerization of olefins | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1991-07-10 | — | — | EP | disclosed |