Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.52 |
| ▸ | EHMT1 | Q9H9B1 | 1/20 | 0.52 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 4/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL35924 | 0.89 | — | — | |
| Ammonia Solution, Strong SCHEMBL7972300 | 0.87 | — | — | |
| Hydrochloric Acid SCHEMBL10707245 | 0.87 | — | — | |
| SCHEMBL28128254 | 0.87 | — | — | |
| Bicarbonate SCHEMBL16975005 | 0.83 | ALDH1A1 (0.53) | EHMT2EHMT1APOBEC3GALDH1A1KMT2A | |
| Ethylene Glycol SCHEMBL3505769 | 0.83 | EHMT2 (0.77) | EHMT2EHMT1APOBEC3GALDH1A1KMT2A | |
| Pyridine SCHEMBL27614389 | 0.81 | EHMT2 (0.54) | EHMT2EHMT1APOBEC3GALDH1A1KMT2A | |
| Ethylamine SCHEMBL18229942 | 0.80 | EHMT2 (0.48) | EHMT2EHMT1APOBEC3GALDH1A1KMT2A | |
| Carbamic Acid SCHEMBL16975014 | 0.80 | ALDH1A1 (0.50) | EHMT2EHMT1APOBEC3GALDH1A1KMT2A | |
| Propionic Acid SCHEMBL6660723 | 0.80 | ALDH1A1 (0.54) | EHMT2EHMT1APOBEC3GALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017177055-A1 | CYCLODEXTRIN-BASED POLYMERS FOR THERAPEUTIC DELIVERY | ZHAO LIANG (US) | 2017-10-12 | — | — | WO | disclosed |
| US-9150837-B2 | Polyethylene glycolated superoxide dismutase mimetics | GALERA LABS LLC (US) | 2015-10-06 | — | — | US | disclosed |
| US-20130287696-A1 | POLYETHYLENE GLYCOLATED SUPEROXIDE DISMUTASE MIMETICS | GALERA THERAPEUTICS, LLC | 2013-10-31 | — | — | US | disclosed |
| US-20120301403-A1 | POLYETHYLENE GLYCOLATED SUPEROXIDE DISMUTASE MIMETICS | GALERA THERAPEUTICS, LLC (US) | 2012-11-29 | — | — | US | disclosed |
| US-8217166-B2 | Polyethylene glycolated superoxide dismutase mimetics | GALERA THERAPEUTICS, LLC (US) | 2012-07-10 | — | — | US | disclosed |
| US-20080318917-A1 | POLYETHYLENE GLYCOLATED SUPEROXIDE DISMUTASE MIMETICS | GALERA THERAPEUTICS, LLC | 2008-12-25 | — | — | US | disclosed |
| WO-2006069326-A2 | POLYETHYLENE GLYCOLATED SUPEROXIDE DISMUTASE MIMETICS | METAPHORE PHARMACEUTICALS, INC. (US) | 2006-06-29 | — | — | WO | disclosed |
| EP-1165047-A1 | FUSOGENIC LIPIDS AND VESICLES | ISIS PHARMACEUTICALS, INC. (US) | 2002-01-02 | — | — | EP | disclosed |
| WO-2000059474-A1 | FUSOGENIC LIPIDS AND VESICLES | ISIS PHARMACEUTICALS, INC. (US) | 2000-10-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080318917-A1 | POLYETHYLENE GLYCOLATED SUPEROXIDE DISMUTASE MIMETICS | SOD1, SOD3, CAT | EHMT2 2322/4885EHMT1 1835/4885APOBEC3G 1480/4885 |
| US-20120301403-A1 | POLYETHYLENE GLYCOLATED SUPEROXIDE DISMUTASE MIMETICS | SOD1, SOD3, CAT | EHMT2 2703/4885EHMT1 2254/4885APOBEC3G 1376/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.