Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.52 |
| ▸ | GNAI3 | P08754 | 2/20 | 0.43 |
| ▸ | GNAO1 | P09471 | 2/20 | 0.43 |
| ▸ | GNAI1 | P63096 | 2/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.40 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL508910 | 1.00 | — | — | |
| SCHEMBL4420470 | 0.90 | PAOX (0.53) | HRH3GNAI3GNAO1GNAI1PAOX | |
| SCHEMBL5405813 | 0.90 | PAOX (0.53) | HRH3GNAI3GNAO1GNAI1PAOX | |
| SCHEMBL5385764 | 0.90 | PAOX (0.53) | HRH3GNAI3GNAO1GNAI1PAOX | |
| SCHEMBL5405613 | 0.90 | PAOX (0.53) | HRH3GNAI3GNAO1GNAI1PAOX | |
| SCHEMBL5397114 | 0.89 | HRH3 (0.70) | HRH3CXCR4ALOX15MAPT | |
| SCHEMBL5397440 | 0.89 | HRH3 (0.70) | HRH3CXCR4ALOX15MAPT | |
| SCHEMBL5388937 | 0.89 | HRH3 (0.70) | HRH3CXCR4ALOX15MAPT | |
| SCHEMBL3386979 | 0.89 | HRH3 (0.62) | HRH3CXCR4ALOX15MAPT | |
| SCHEMBL6716650 | 0.89 | HRH3 (0.70) | HRH3CXCR4ALOX15MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 135 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4313567-A1 | METHOD FOR MAKING PHOTOCHROMIC CONTACT LENSES | Alcon Inc. (CH) | 2024-02-07 | — | — | EP | claimed |
| EP-4304842-A1 | METHOD FOR MAKING PHOTOFUNCTIONAL CONTACT LENSES | Alcon Inc. (CH) | 2024-01-17 | — | — | EP | claimed |
| EP-4304843-A1 | METHOD FOR MAKING PHOTOCHROMIC CONTACT LENSES | Alcon Inc. (CH) | 2024-01-17 | — | — | EP | claimed |
| EP-3976362-B1 | METHOD FOR MAKING OPAQUE COLORED SILICONE HYDROGEL CONTACT LENSES | ALCON INC (CH) | 2023-06-07 | — | — | EP | claimed |
| EP-4158392-A1 | METHOD FOR MAKING PHOTOCHROMIC CONTACT LENSES | Alcon Inc. (CH) | 2023-04-05 | — | — | EP | claimed |
| WO-2022189941-A1 | METHOD FOR MAKING PHOTOCHROMIC CONTACT LENSES | ALCON INC. (CH) | 2022-09-15 | — | — | WO | claimed |
| US-20220281193-A1 | METHOD FOR MAKING PHOTOFUNCTIONAL CONTACT LENSES | ALCON INC. (CH) | 2022-09-08 | — | — | US | claimed |
| US-20210371731-A1 | METHOD FOR MAKING PHOTOCHROMIC CONTACT LENSES | ALCON INC. (CH) | 2021-12-02 | — | — | US | claimed |
| WO-2020240440-A1 | METHOD FOR MAKING OPAQUE COLORED SILICONE HYDROGEL CONTACT LENSES | ALCON INC. (CH) | 2020-12-03 | — | — | WO | claimed |
| US-20200376787-A1 | METHOD FOR MAKING OPAQUE COLORED SILICONE HYDROGEL CONTACT LENSES | ALCON INC. (CH) | 2020-12-03 | — | — | US | claimed |
| US-8557940-B2 | Amphiphilic polysiloxane prepolymers and uses thereof | NOVARTIS AG (CH) | 2013-10-15 | — | — | US | claimed |
| EP-2625218-A1 | WATER-PROCESSABLE SILICONE-CONTAINING PREPOLYMERS AND USES THEREOF | Novartis AG (CH) | 2013-08-14 | — | — | EP | claimed |
| EP-2625217-A1 | CHAIN-EXTENDED POLYSILOXANE CROSSLINKERS WITH DANGLING HYDROPHILIC POLYMER CHAINS | Novartis AG (CH) | 2013-08-14 | — | — | EP | claimed |
| EP-2598937-A2 | AMPHIPHILIC POLYSILOXANE PREPOLYMERS AND USES THEREOF | Novartis AG (CH) | 2013-06-05 | — | — | EP | claimed |
| EP-2480927-A1 | PREPOLYMERS SUITABLE FOR MAKING ULTRA-VIOLET ABSORBING CONTACT LENSES | Novartis AG (CH) | 2012-08-01 | — | — | EP | claimed |
| WO-2012047964-A1 | CHAIN-EXTENDED POLYSILOXANE CROSSLINKERS WITH DANGLING HYDROPHILIC POLYMER CHAINS | NOVARTIS AG (CH) | 2012-04-12 | — | — | WO | claimed |
| WO-2012047969-A1 | WATER-PROCESSABLE SILICONE-CONTAINING PREPOLYMERS AND USES THEREOF | NOVARTIS AG (CH) | 2012-04-12 | — | — | WO | claimed |
| US-20120029111-A1 | AMPHIPHILIC POLYSILOXANE PREPOLYMERS AND USES THEREOF | ALCON INC. (CH) | 2012-02-02 | — | — | US | claimed |
| WO-2012016097-A2 | AMPHIPHILIC POLYSILOXANE PREPOLYMERS AND USES THEREOF | NOVARTIS AG (CH) | 2012-02-02 | — | — | WO | claimed |
| WO-2011034801-A1 | PREPOLYMERS SUITABLE FOR MAKING ULTRA-VIOLET ABSORBING CONTACT LENSES | NOVARTIS AG (CH) | 2011-03-24 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120029111-A1 | AMPHIPHILIC POLYSILOXANE PREPOLYMERS AND USES THEREOF | PIGS, ELOVL1, HACD2 | HRH3 1807/4885GNAI3 2050/4885GNAO1 2106/4885 |
| US-20200376787-A1 | METHOD FOR MAKING OPAQUE COLORED SILICONE HYDROGEL CONTACT LENSES | COIL, CRYAB, CRYAA | HRH3 1311/4885GNAI3 3040/4885GNAO1 4407/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.