Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | HPRT1 | P00492 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.43 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3251732 | 0.79 | ALDH1A1 (0.44) | ALDH1A1KDM4EHSD17B10CYP2A6TSHR | |
| SCHEMBL23054105 | 0.79 | CYP2A6 (0.44) | ALDH1A1KDM4EHSD17B10CYP2A6TSHR | |
| SCHEMBL30220310 | 0.79 | CYP2A6 (0.44) | ALDH1A1KDM4EHSD17B10CYP2A6TSHR | |
| SCHEMBL29977029 | 0.79 | CYP2A6 (0.44) | ALDH1A1KDM4EHSD17B10CYP2A6TSHR | |
| Methyl Alcohol SCHEMBL11298761 | 0.78 | MAP2K2 (0.37) | ALDH1A1KDM4EHSD17B10CYP2A6HPRT1 | |
| SCHEMBL646163 | 0.77 | CA1 (0.52) | ALDH1A1KDM4EHSD17B10CYP2A6TSHR | |
| SCHEMBL1392608 | 0.75 | ALDH1A1 (0.45) | ALDH1A1KDM4EHSD17B10CYP2A6TSHR | |
| SCHEMBL2419451 | 0.75 | ALDH1A1 (0.46) | ALDH1A1KDM4EHSD17B10CYP2A6TSHR | |
| SCHEMBL5251868 | 0.75 | ALDH1A1 (0.48) | ALDH1A1KDM4EHSD17B10CYP2A6TSHR | |
| SCHEMBL7306027 | 0.75 | CA1 (0.47) | ALDH1A1KDM4EHSD17B10CYP2A6TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4319754-A1 | COMBINATION THERAPIES USING PRMT5 INHIBITORS FOR THE TREATMENT OF CANCER | Mirati Therapeutics, Inc. (US) | 2024-02-14 | — | — | EP | disclosed |
| US-8129554-B2 | Metal complexes | MERCK PATENT GMBH (DE) | 2012-03-06 | — | — | US | disclosed |
| EP-1915386-B1 | METAL COMPLEX | MERCK PATENT GMBH (DE) | 2011-06-08 | — | — | EP | disclosed |
| US-20090118453-A1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2009-05-07 | — | — | US | disclosed |
| EP-1915386-A1 | METAL COMPLEX | Merck Patent GmbH (DE) | 2008-04-30 | — | — | EP | disclosed |
| WO-2007092391-A1 | ANDROGEN RECEPTOR MODULATORS AND METHODS OF TREATING DISEASE USING THE SAME | ACADIA PHARMACEUTICALS INC. (US) | 2007-08-16 | — | — | WO | disclosed |
| WO-2007019942-A1 | METAL COMPLEX | MERCK PATENT GMBH (DE) | 2007-02-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090118453-A1 | METAL COMPLEXES | SOD1, AP1M1, AP2M1 | ALDH1A1 366/4885KDM4E 3254/4885HSD17B10 2072/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.