Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 known ✓ | Q99720 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | GUSB | P08236 | 2/20 | 0.37 |
| ▸ | EBP | Q15125 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 4/20 | 0.36 |
| ▸ | RAB9A | P51151 | 4/20 | 0.36 |
| ▸ | HTT | P42858 | 3/20 | 0.36 |
| ▸ | GALR3 | O60755 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | ATM | Q13315 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | RAD52 | P43351 | 1/20 | 0.36 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL574729 | 1.00 | ALDH1A1 (0.39) | ALDH1A1CYP1A2CYP2D6CYP2C19GUSB | |
| Bromide SCHEMBL2890414 | 1.00 | ALDH1A1 (0.39) | ALDH1A1CYP1A2CYP2D6CYP2C19GUSB | |
| Bromide SCHEMBL235205 | 1.00 | ALDH1A1 (0.39) | ALDH1A1CYP1A2CYP2D6CYP2C19GUSB | |
| Bromide SCHEMBL2530782 | 1.00 | ALDH1A1 (0.39) | ALDH1A1CYP1A2CYP2D6CYP2C19GUSB | |
| Bromide SCHEMBL5087905 | 1.00 | ALDH1A1 (0.39) | ALDH1A1CYP1A2CYP2D6CYP2C19GUSB | |
| Bromide SCHEMBL5091786 | 1.00 | ALDH1A1 (0.39) | ALDH1A1CYP1A2CYP2D6CYP2C19GUSB | |
| Bromide SCHEMBL571828 | 1.00 | ALDH1A1 (0.39) | ALDH1A1CYP1A2CYP2D6CYP2C19GUSB | |
| Bromide SCHEMBL5084974 | 1.00 | ALDH1A1 (0.39) | ALDH1A1CYP1A2CYP2D6CYP2C19GUSB | |
| Bromide SCHEMBL466203 | 1.00 | ALDH1A1 (0.39) | ALDH1A1CYP1A2CYP2D6CYP2C19GUSB | |
| Bromide SCHEMBL31066878 | 1.00 | ALDH1A1 (0.39) | ALDH1A1CYP1A2CYP2D6CYP2C19GUSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109456561-A | Regenerated anti-aging HIPS plastic | 东莞市宇豪塑胶科技有限公司 | 2019-03-12 | — | — | CN | claimed |
| CN-107743502-A | Solidification composition filling | 爱客多有限公司 | 2018-02-27 | — | — | CN | claimed |
| CN-107743502-B | Curing composition | 爱客多有限公司 | 2020-08-28 | — | — | CN | disclosed |
| CN-104617338-B | Sodium rechargeable battery comprising forming slotted graphite felt | SK新技术株式会社 | 2019-11-12 | — | — | CN | disclosed |
| CN-104600352-B | Sodium rechargeable battery with the graphite felt for forming air vent channel | SK INNOVATION CO.,LTD. (KR) | 2019-11-01 | — | — | CN | disclosed |
| US-20190111423-A1 | DEVICES AND METHODS FOR AUTONOMOUS MEASUREMENTS | CALIFORNIA INSTITUTE OF TECHNOLOGY | 2019-04-18 | — | — | US | disclosed |
| CN-109456561-A | Regenerated anti-aging HIPS plastic | 东莞市宇豪塑胶科技有限公司 | 2019-03-12 | — | — | CN | disclosed |
| US-10207269-B2 | System and method for movement and timing control | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2019-02-19 | — | — | US | disclosed |
| EP-2839260-B1 | FLUIDIC DEVICES AND SYSTEMS FOR SAMPLE PREPARATION OR AUTONOMOUS ANALYSIS | TALIS BIOMEDICAL CORP (US) | 2018-07-18 | — | — | EP | disclosed |
| CN-107743502-A | Solidification composition filling | 爱客多有限公司 | 2018-02-27 | — | — | CN | disclosed |
| US-9822356-B2 | Fluidic devices and systems for sample preparation or autonomous analysis | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2017-11-21 | — | — | US | disclosed |
| US-20160263577-A1 | SYSTEM AND METHOD FOR MOVEMENT AND TIMING CONTROL | CALIFORNIA INSTITUTE OF TECHNOLOGY | 2016-09-15 | — | — | US | disclosed |
| US-20150259571-A1 | LIGNIN MEMBRANES AND COATINGS | EMPIRE TECHNOLOGY DEVELOPMENT LLC | 2015-09-17 | — | — | US | disclosed |
| CN-104600352-A | Sodium secondary battery having graphite felt with pore channels | SK INNOVATION CO LTD | 2015-05-06 | — | — | CN | disclosed |
| CN-104428651-A | Fluidic device and system for sample preparation or autonomous analysis | SLIPCHIP LLC | 2015-03-18 | — | — | CN | disclosed |
| WO-2014035498-A1 | LIGNIN MEMBRANES AND COATINGS | EMPIRE TECHNOLOGY DEVELOPMENT LLC (US) | 2014-03-06 | — | — | WO | disclosed |
| US-20130309679-A1 | FLUIDIC DEVICES AND SYSTEMS FOR SAMPLE PREPARATION OR AUTONOMOUS ANALYSIS | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2013-11-21 | — | — | US | disclosed |
| US-20130281316-A1 | SLIP-INDUCED COMPARTMENTALIZATION | SlipChip, LLC (US) | 2013-10-24 | — | — | US | disclosed |
| US-20130280725-A1 | FLUIDIC DEVICES FOR BIOSPECIMEN PRESERVATION | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2013-10-24 | — | — | US | disclosed |
| US-20080214386-A1 | Stability; easily separated from solution; surface treatment of catalyst with Group seven compound; reacting epoxide with carbon dioxide | NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) | 2008-09-04 | — | — | US | disclosed |