Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 known ✓ | Q99720 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | GUSB | P08236 | 2/20 | 0.37 |
| ▸ | EBP | Q15125 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 4/20 | 0.36 |
| ▸ | RAB9A | P51151 | 4/20 | 0.36 |
| ▸ | HTT | P42858 | 3/20 | 0.36 |
| ▸ | GALR3 | O60755 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | ATM | Q13315 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | RAD52 | P43351 | 1/20 | 0.36 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL5087811 | 1.00 | ALDH1A1 (0.39) | ALDH1A1CYP1A2CYP2D6CYP2C19GUSB | |
| Bromide SCHEMBL574729 | 1.00 | ALDH1A1 (0.39) | ALDH1A1CYP1A2CYP2D6CYP2C19GUSB | |
| Bromide SCHEMBL2890414 | 1.00 | ALDH1A1 (0.39) | ALDH1A1CYP1A2CYP2D6CYP2C19GUSB | |
| Bromide SCHEMBL235205 | 1.00 | ALDH1A1 (0.39) | ALDH1A1CYP1A2CYP2D6CYP2C19GUSB | |
| Bromide SCHEMBL2530782 | 1.00 | ALDH1A1 (0.39) | ALDH1A1CYP1A2CYP2D6CYP2C19GUSB | |
| Bromide SCHEMBL5087905 | 1.00 | ALDH1A1 (0.39) | ALDH1A1CYP1A2CYP2D6CYP2C19GUSB | |
| Bromide SCHEMBL5091786 | 1.00 | ALDH1A1 (0.39) | ALDH1A1CYP1A2CYP2D6CYP2C19GUSB | |
| Bromide SCHEMBL571828 | 1.00 | ALDH1A1 (0.39) | ALDH1A1CYP1A2CYP2D6CYP2C19GUSB | |
| Bromide SCHEMBL5084974 | 1.00 | ALDH1A1 (0.39) | ALDH1A1CYP1A2CYP2D6CYP2C19GUSB | |
| Bromide SCHEMBL31066878 | 1.00 | ALDH1A1 (0.39) | ALDH1A1CYP1A2CYP2D6CYP2C19GUSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 385 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250188048-A1 | METHOD FOR PREPARING 2,5-FURANDICARBOXYLIC ACID COMPOUND | JIANGSU CELLURANICS NEW MATERIAL TECHNOLOGY CO., LTD. (CN) | 2025-06-12 | — | — | US | claimed |
| CN-119912872-A | Anti-pollution flashover coating composition and application thereof | 成都万通瑞华材料科技有限公司 | 2025-05-02 | — | — | CN | claimed |
| CN-119771415-A | Petal-shaped Co-Mg-Al-LDH, and preparation method and application thereof | 河南农业大学 | 2025-04-08 | — | — | CN | claimed |
| CN-119700885-A | Veterinary traditional Chinese medicine granule for preventing and treating atypical bursa of Fabricius of poultry and application thereof | 石家庄市九洲兽药有限公司 | 2025-03-28 | — | — | CN | claimed |
| CN-116381109-B | Method for simultaneously detecting six trace herbicides in water | 浙江省林业科学研究院 | 2025-03-25 | — | — | CN | claimed |
| CN-119505483-A | Epoxy resin composite material and application thereof | 内蒙古赛勒商贸有限公司 | 2025-02-25 | — | — | CN | claimed |
| CN-119504596-A | Preparation method and application of functional lithium battery anode AT9 coating additive material | 安徽得壹能源科技有限公司 | 2025-02-25 | — | — | CN | claimed |
| CN-119219533-A | Wool hydrolysis method | 峨眉山市龙腾生物科技有限公司 | 2024-12-31 | — | — | CN | claimed |
| EP-4477651-A1 | METHOD FOR PREPARING 2,5-FURANDICARBOXYLIC ACID COMPOUND | Jiangsu Celluranics New Material Technology Co., Ltd. (CN) | 2024-12-18 | — | — | EP | claimed |
| CN-117000061-B | Polyamide thin layer composite nanofiltration membrane and preparation method and application thereof | 杭州师范大学 | 2024-08-30 | — | — | CN | claimed |
| EP-2089414-B1 | USE OF IONIC LIQUIDS FOR MEMBRANE PROTEIN EXTRACTION | MERCK PATENT GMBH (DE) | 2013-03-06 | — | — | EP | claimed |
| US-8143381-B2 | Use of ionic liquids for membrane protein extraction | MERCK PATENT GMBH (DE) | 2012-03-27 | — | — | US | claimed |
| US-20120052572-A1 | COMPOSITIONS FOR STABILIZING DNA, RNA AND PROTEINS IN BLOOD AND OTHER BIOLOGICAL SAMPLES DURING SHIPPING AND STORAGE AT AMBIENT TEMPERATURES | EXACT SCIENCES CORPORATION | 2012-03-01 | — | — | US | claimed |
| WO-2012018639-A2 | COMPOSITIONS FOR STABILIZING DNA, RNA AND PROTEINS IN SALIVA AND OTHER BIOLOGICAL SAMPLES DURING SHIPPING AND STORAGE AT AMBIENT TEMPERATURES | BIOMATRICA, INC. (US) | 2012-02-09 | — | — | WO | claimed |
| WO-2012018638-A2 | COMPOSITIONS FOR STABILIZING DNA, RNA AND PROTEINS IN BLOOD AND OTHER BIOLOGICAL SAMPLES DURING SHIPPING AND STORAGE AT AMBIENT TEMPERATURES | BIOMATRICA, INC. (US) | 2012-02-09 | — | — | WO | claimed |
| US-8071080-B2 | May be imidazolium, pyrazolium, pyridinium, pyrimidinium or tetraalkylphosphonium salts; washing (cleaning) and/or conditioning keratin materials, and especially the hair. | L'OREAL (FR) | 2011-12-06 | — | — | US | claimed |
| EP-1362572-B2 | Use of at least one particular organic salt for cleansing and/or conditioning keratinous materials, use of a particular organic salt as conditioning agent for said materials and process for cosmetic treatment | OREAL (FR) | 2011-08-17 | — | — | EP | claimed |
| US-20100029917-A1 | USE OF IONIC LIQUIDS FOR MEMBRANE PROTEIN EXTRACTION | MERCK PATENT GMBH (DE) | 2010-02-04 | — | — | US | claimed |
| EP-1362572-B1 | Use of at least one particular organic salt for cleansing and/or conditioning keratinous materials, use of a particular organic salt as conditioning agent for said materials and process for cosmetic treatment | OREAL (FR) | 2008-04-16 | — | — | EP | claimed |
| US-20040005286-A1 | Organic salt conditioner, organic salt-containing composition, and uses thereof | L'OREAL (FR) | 2004-01-08 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040005286-A1 | Organic salt conditioner, organic salt-containing composition, and uses thereof | KRT18, HCN4, PRKDC | SIGMAR1 1106/4885ALDH1A1 1213/4885CYP1A2 2721/4885 |
| US-20100029917-A1 | USE OF IONIC LIQUIDS FOR MEMBRANE PROTEIN EXTRACTION | APMAP, VAMP8, VAMP7 | SIGMAR1 3646/4885ALDH1A1 4833/4885CYP1A2 4880/4885 |
| US-20250188048-A1 | METHOD FOR PREPARING 2,5-FURANDICARBOXYLIC ACID COMPOUND | HPD, DPYD, PGD | SIGMAR1 4038/4885ALDH1A1 624/4885CYP1A2 850/4885 |
| US-20120052572-A1 | COMPOSITIONS FOR STABILIZING DNA, RNA AND PROTEINS IN BLOOD AND OTHER BIOLOGICAL SAMPLES DURING SHIPPING AND STORAGE AT AMBIENT TEMPERATURES | HNRNPD, HNRNPDL, HNRNPL | SIGMAR1 3550/4885ALDH1A1 3155/4885CYP1A2 4597/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.