Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 known ✓ | Q99720 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | GUSB | P08236 | 2/20 | 0.37 |
| ▸ | EBP | Q15125 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 4/20 | 0.36 |
| ▸ | RAB9A | P51151 | 4/20 | 0.36 |
| ▸ | HTT | P42858 | 3/20 | 0.36 |
| ▸ | GALR3 | O60755 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | ATM | Q13315 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | RAD52 | P43351 | 1/20 | 0.36 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL5087811 | 1.00 | ALDH1A1 (0.39) | ALDH1A1CYP1A2CYP2D6CYP2C19GUSB | |
| Bromide SCHEMBL574729 | 1.00 | ALDH1A1 (0.39) | ALDH1A1CYP1A2CYP2D6CYP2C19GUSB | |
| Bromide SCHEMBL2890414 | 1.00 | ALDH1A1 (0.39) | ALDH1A1CYP1A2CYP2D6CYP2C19GUSB | |
| Bromide SCHEMBL235205 | 1.00 | ALDH1A1 (0.39) | ALDH1A1CYP1A2CYP2D6CYP2C19GUSB | |
| Bromide SCHEMBL2530782 | 1.00 | ALDH1A1 (0.39) | ALDH1A1CYP1A2CYP2D6CYP2C19GUSB | |
| Bromide SCHEMBL5087905 | 1.00 | ALDH1A1 (0.39) | ALDH1A1CYP1A2CYP2D6CYP2C19GUSB | |
| Bromide SCHEMBL5091786 | 1.00 | ALDH1A1 (0.39) | ALDH1A1CYP1A2CYP2D6CYP2C19GUSB | |
| Bromide SCHEMBL5084974 | 1.00 | ALDH1A1 (0.39) | ALDH1A1CYP1A2CYP2D6CYP2C19GUSB | |
| Bromide SCHEMBL466203 | 1.00 | ALDH1A1 (0.39) | ALDH1A1CYP1A2CYP2D6CYP2C19GUSB | |
| Bromide SCHEMBL31066878 | 1.00 | ALDH1A1 (0.39) | ALDH1A1CYP1A2CYP2D6CYP2C19GUSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 580 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260078235-A1 | METHOD FOR POLYURETHANE DEPOLYMERIZATION | UNIV MURCIA (ES) | 2026-03-19 | — | — | US | claimed |
| CN-121571186-A | N-containing material3G-C of C vacancy3N4Base composite catalyst and preparation method and application thereof | 南昌航空大学 | 2026-02-27 | — | — | CN | claimed |
| CN-120137717-A | Preparation method of environment-friendly conductive lubricating grease based on ionic liquid additive | 中国科学院兰州化学物理研究所 | 2025-06-13 | — | — | CN | claimed |
| EP-4556514-A1 | METHOD FOR POLYURETHANE DEPOLYMERIZATION | Universidad de Murcia (ES) | 2025-05-21 | — | — | EP | claimed |
| CN-119912872-A | Anti-pollution flashover coating composition and application thereof | 成都万通瑞华材料科技有限公司 | 2025-05-02 | — | — | CN | claimed |
| WO-2025089464-A1 | COMPOSITION FOR CLEANING SEPARATOR AND MANUFACTURING METHOD THEREOF | 주식회사 에이엔폴리 | 2025-05-01 | — | — | WO | claimed |
| CN-119837947-A | Preparation method of bone hyperplasia eliminating medicine | 南昌华太生物科技开发有限公司 | 2025-04-18 | — | — | CN | claimed |
| CN-119630729-A | Method for depolymerizing polyurethane | 穆尔西亚大学 | 2025-03-14 | — | — | CN | claimed |
| CN-119504596-A | Preparation method and application of functional lithium battery anode AT9 coating additive material | 安徽得壹能源科技有限公司 | 2025-02-25 | — | — | CN | claimed |
| CN-119505483-A | Epoxy resin composite material and application thereof | 内蒙古赛勒商贸有限公司 | 2025-02-25 | — | — | CN | claimed |
| US-20160340467-A1 | CURING COMPOSITIONS | AQDOT LIMITED (GB) | 2016-11-24 | — | — | US | claimed |
| EP-3095804-A1 | CURING COMPOSITIONS | Aqdot Ltd (GB) | 2016-11-23 | — | — | EP | claimed |
| CN-106029621-A | Process for oxidation of alkyl aromatic compound to aromatic carboxylic acid | 信实工业公司 | 2016-10-12 | — | — | CN | claimed |
| EP-2063985-B1 | IONIC ADDITIVE FOR CATALYSIS IN BIPHASIC REACTION SYSTEMS | UNIV ST ANDREWS (GB) | 2016-04-20 | — | — | EP | claimed |
| US-9126848-B2 | Synthesis of nanoparticles by means of ionic liquids | Leibniz-Insitut fuer Neue Materialien gemeinnuetzige GmbH (DE) | 2015-09-08 | — | — | US | claimed |
| US-20130209997-A1 | COMPOSITIONS FOR STABILIZING DNA, RNA AND PROTEINS IN SALIVA AND OTHER BIOLOGICAL SAMPLES DURING SHIPPING AND STORAGE AT AMBIENT TEMPERATURES | BIOMATRICA, INC. (US) | 2013-08-15 | — | — | US | claimed |
| EP-2598661-A2 | COMPOSITIONS FOR STABILIZING DNA, RNA AND PROTEINS IN SALIVA AND OTHER BIOLOGICAL SAMPLES DURING SHIPPING AND STORAGE AT AMBIENT TEMPERATURES | Biomatrica, INC. (US) | 2013-06-05 | — | — | EP | claimed |
| WO-2012018639-A2 | COMPOSITIONS FOR STABILIZING DNA, RNA AND PROTEINS IN SALIVA AND OTHER BIOLOGICAL SAMPLES DURING SHIPPING AND STORAGE AT AMBIENT TEMPERATURES | BIOMATRICA, INC. (US) | 2012-02-09 | — | — | WO | claimed |
| WO-2007134183-A2 | CHEMICAL REAGENT DELIVERY SYSTEM UTILIZING IONIC LIQUID STORAGE MEDIUM | ADVANCED TECHNOLOGY MATERIALS, INC. (US) | 2007-11-22 | — | — | WO | claimed |
| US-20050131118-A1 | Ionic liquids containing a sulfonate anion | PNC BANK, NATIONAL ASSOCIATION | 2005-06-16 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050131118-A1 | Ionic liquids containing a sulfonate anion | MSN, TST, SQOR | SIGMAR1 359/4885ALDH1A1 2093/4885CYP1A2 2666/4885 |
| US-20260078235-A1 | METHOD FOR POLYURETHANE DEPOLYMERIZATION | FGB, POLR2B, POLB | SIGMAR1 1524/4885ALDH1A1 3013/4885CYP1A2 3587/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.