Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 known ✓ | Q99720 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | GUSB | P08236 | 2/20 | 0.37 |
| ▸ | EBP | Q15125 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 4/20 | 0.36 |
| ▸ | RAB9A | P51151 | 4/20 | 0.36 |
| ▸ | HTT | P42858 | 3/20 | 0.36 |
| ▸ | GALR3 | O60755 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | ATM | Q13315 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | RAD52 | P43351 | 1/20 | 0.36 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL5087811 | 1.00 | ALDH1A1 (0.39) | ALDH1A1CYP1A2CYP2D6CYP2C19GUSB | |
| Bromide SCHEMBL574729 | 1.00 | ALDH1A1 (0.39) | ALDH1A1CYP1A2CYP2D6CYP2C19GUSB | |
| Bromide SCHEMBL2890414 | 1.00 | ALDH1A1 (0.39) | ALDH1A1CYP1A2CYP2D6CYP2C19GUSB | |
| Bromide SCHEMBL2530782 | 1.00 | ALDH1A1 (0.39) | ALDH1A1CYP1A2CYP2D6CYP2C19GUSB | |
| Bromide SCHEMBL5087905 | 1.00 | ALDH1A1 (0.39) | ALDH1A1CYP1A2CYP2D6CYP2C19GUSB | |
| Bromide SCHEMBL5091786 | 1.00 | ALDH1A1 (0.39) | ALDH1A1CYP1A2CYP2D6CYP2C19GUSB | |
| Bromide SCHEMBL571828 | 1.00 | ALDH1A1 (0.39) | ALDH1A1CYP1A2CYP2D6CYP2C19GUSB | |
| Bromide SCHEMBL5084974 | 1.00 | ALDH1A1 (0.39) | ALDH1A1CYP1A2CYP2D6CYP2C19GUSB | |
| Bromide SCHEMBL466203 | 1.00 | ALDH1A1 (0.39) | ALDH1A1CYP1A2CYP2D6CYP2C19GUSB | |
| Bromide SCHEMBL31066878 | 1.00 | ALDH1A1 (0.39) | ALDH1A1CYP1A2CYP2D6CYP2C19GUSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 949 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-121769280-B | Micro zinc-iodine battery with wide temperature range and preparation method thereof | 苏州大学 | 2026-05-12 | — | — | CN | claimed |
| US-20260078235-A1 | METHOD FOR POLYURETHANE DEPOLYMERIZATION | UNIV MURCIA (ES) | 2026-03-19 | — | — | US | claimed |
| US-20250188048-A1 | METHOD FOR PREPARING 2,5-FURANDICARBOXYLIC ACID COMPOUND | JIANGSU CELLURANICS NEW MATERIAL TECHNOLOGY CO., LTD. (CN) | 2025-06-12 | — | — | US | claimed |
| CN-120041960-A | Chinlon 66 cord fabric and preparation method thereof | 江苏弘盛新材料股份有限公司 | 2025-05-27 | — | — | CN | claimed |
| CN-120022745-A | High-permeability roll-type ultrafiltration membrane based on ionic liquid and preparation method thereof | 天津工业大学 | 2025-05-23 | — | — | CN | claimed |
| EP-4556514-A1 | METHOD FOR POLYURETHANE DEPOLYMERIZATION | Universidad de Murcia (ES) | 2025-05-21 | — | — | EP | claimed |
| CN-119193246-B | Cleaning agent for electric tea boiler of motor car and preparation method of cleaning agent | 广州市凯之达化工有限公司 | 2025-05-16 | — | — | CN | claimed |
| CN-119954185-A | Preparation method of high-purity ammonium fluoberyllium acid | 广西太洋科技有限公司 | 2025-05-09 | — | — | CN | claimed |
| CN-119630729-A | Method for depolymerizing polyurethane | 穆尔西亚大学 | 2025-03-14 | — | — | CN | claimed |
| CN-119504596-A | Preparation method and application of functional lithium battery anode AT9 coating additive material | 安徽得壹能源科技有限公司 | 2025-02-25 | — | — | CN | claimed |
| US-8329022-B2 | Method for quantifying a chemical substance by substitutional stripping voltammetry and a sensor chip used therefor | PANASONIC CORPORATION (JP) | 2012-12-11 | — | — | US | claimed |
| US-20120216604-A1 | METHOD FOR QUANTIFYING A CHEMICAL SUBSTANCE BY SUBSTITUTIONAL STRIPPING VOLTAMMETRY AND A SENSOR CHIP USED THEREFOR | PANASONIC CORPORATION (JP) | 2012-08-30 | — | — | US | claimed |
| US-20120052572-A1 | COMPOSITIONS FOR STABILIZING DNA, RNA AND PROTEINS IN BLOOD AND OTHER BIOLOGICAL SAMPLES DURING SHIPPING AND STORAGE AT AMBIENT TEMPERATURES | EXACT SCIENCES CORPORATION | 2012-03-01 | — | — | US | claimed |
| WO-2012018639-A2 | COMPOSITIONS FOR STABILIZING DNA, RNA AND PROTEINS IN SALIVA AND OTHER BIOLOGICAL SAMPLES DURING SHIPPING AND STORAGE AT AMBIENT TEMPERATURES | BIOMATRICA, INC. (US) | 2012-02-09 | — | — | WO | claimed |
| EP-2415913-A1 | PROCESSES FOR PRODUCING CARBON FIBER, THE FILAMENT THEREOF, AND PRE-OXIDIZED FIBER | Donghua University (CN) | 2012-02-08 | — | — | EP | claimed |
| WO-2012012047-A2 | PROCESS FOR PRODUCING TEREPHTHALIC ACID | UOP LLC (US) | 2012-01-26 | — | — | WO | claimed |
| WO-2012005902-A2 | PROCESS FOR PURIFYING TEREPHTHALIC ACID | UOP LLC (US) | 2012-01-12 | — | — | WO | claimed |
| US-20120004456-A1 | PROCESS FOR PURIFYING TEREPHTHALIC ACID | UOP LLC (US) | 2012-01-05 | — | — | US | claimed |
| US-20120004450-A1 | PROCESS FOR PRODUCING TEREPHTHALIC ACID | BORESKOV INSTITUTE OF CATALYSIS (RU) | 2012-01-05 | — | — | US | claimed |
| WO-2007134183-A2 | CHEMICAL REAGENT DELIVERY SYSTEM UTILIZING IONIC LIQUID STORAGE MEDIUM | ADVANCED TECHNOLOGY MATERIALS, INC. (US) | 2007-11-22 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250188048-A1 | METHOD FOR PREPARING 2,5-FURANDICARBOXYLIC ACID COMPOUND | HPD, DPYD, PGD | SIGMAR1 4038/4885ALDH1A1 624/4885CYP1A2 850/4885 |
| US-20120052572-A1 | COMPOSITIONS FOR STABILIZING DNA, RNA AND PROTEINS IN BLOOD AND OTHER BIOLOGICAL SAMPLES DURING SHIPPING AND STORAGE AT AMBIENT TEMPERATURES | HNRNPD, HNRNPDL, HNRNPL | SIGMAR1 3550/4885ALDH1A1 3155/4885CYP1A2 4597/4885 |
| US-20260078235-A1 | METHOD FOR POLYURETHANE DEPOLYMERIZATION | FGB, POLR2B, POLB | SIGMAR1 1524/4885ALDH1A1 3013/4885CYP1A2 3587/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.