Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2B | P41595 | 8/20 | 0.36 |
| ▸ | HTR2A | P28223 | 5/20 | 0.36 |
| ▸ | HTR2C | P28335 | 5/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | ACACB | O00763 | 1/20 | 0.32 |
| ▸ | C5AR1 | P21730 | 2/20 | 0.32 |
| ▸ | GPR183 | P32249 | 1/20 | 0.31 |
| ▸ | ADGRF1 | Q5T601 | 1/20 | 0.31 |
| ▸ | GPR65 | Q8IYL9 | 1/20 | 0.31 |
| ▸ | PNMT | P11086 | 2/20 | 0.30 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.30 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.30 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL507314 | 0.68 | LMNA (0.48) | HTR2BHTR2AHTR2CMEN1KMT2A | |
| Succinic Acid SCHEMBL507602 | 0.66 | HTR2C (0.42) | HTR2BHTR2AHTR2CPNMTADRA2A | |
| Succinic Acid SCHEMBL507771 | 0.65 | HTR2B (0.40) | HTR2BHTR2AHTR2CPNMTADRA2A | |
| Succinic Acid SCHEMBL507540 | 0.65 | LMNA (0.45) | HTR2BHTR2AHTR2CMEN1KMT2A | |
| SCHEMBL10228225 | 0.65 | HTR2B (0.48) | HTR2BHTR2AHTR2CPNMTADRA2A | |
| SCHEMBL10228224 | 0.63 | HTR2B (0.48) | HTR2BHTR2AHTR2CMEN1KMT2A | |
| Succinic Acid SCHEMBL2588197 | 0.63 | HTR2B (0.35) | HTR2BHTR2AHTR2CMEN1KMT2A | |
| SCHEMBL13685367 | 0.63 | HTR2B (0.37) | HTR2BHTR2AHTR2CMEN1KMT2A | |
| Succinic Acid SCHEMBL508327 | 0.62 | HTR2B (0.36) | HTR2BHTR2AHTR2CMEN1KMT2A | |
| SCHEMBL2588552 | 0.62 | HTR2B (0.41) | HTR2BHTR2AHTR2CPNMTADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8580780-B2 | 6 substituted 2, 3,4,5 tetrahydro-1H-benzo[d]azepines as 5-HT2C receptor agonist | ELI LILLY AND COMPANY (US) | 2013-11-12 | — | — | US | disclosed |
| US-20120028961-A1 | 6 Substituted 2, 3,4,5 Tetrahydro-1H-Benzo[d]Azepines as 5-HT2c Receptor Agonist | ELI LILLY AND COMPANY (US) | 2012-02-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120028961-A1 | 6 Substituted 2, 3,4,5 Tetrahydro-1H-Benzo[d]Azepines as 5-HT2c Receptor Agonist | HTR2C, HTR4, HTR1A | HTR2B 12/4885HTR2A 4/4885HTR2C 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.