SCHEMBL43850

SCHEMBL43850

O=C(O)CCSC(=O)CN1C(=O)CCC1=O

nearest known ligand 0.39

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.38
RAB9A P51151 1/20 0.38
CYP1A2 P05177 1/20 0.37
TSHR P16473 3/20 0.37
KMT2A Q03164 2/20 0.35
LMNA P02545 2/20 0.35
HSD17B10 Q99714 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
ALDH1A1 P00352 3/20 0.34
ALOX12 P18054 1/20 0.34
MEN1 O00255 1/20 0.33
GAA P10253 1/20 0.33
POLB P06746 1/20 0.33
PTGS1 P23219 4/20 0.33
PTGS2 P35354 4/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL121100 0.81 TSHR (0.40) SMN1; SMN2RAB9ATSHRKMT2ALMNA
SCHEMBL11007672 0.74 LMNA (0.42) SMN1; SMN2RAB9ATSHRKMT2ALMNA
SCHEMBL31440989 0.74 SLC22A6 (0.42) SMN1; SMN2RAB9ATSHRKMT2ALMNA
SCHEMBL236431 0.74 TSHR (0.56) SMN1; SMN2RAB9ATSHRKMT2ALMNA
SCHEMBL1269478 0.73 RAB9A (0.42) SMN1; SMN2RAB9ATSHRKMT2ALMNA
SCHEMBL8859577 0.73 RAB9A (0.36) SMN1; SMN2RAB9ATSHRKMT2ALMNA
SCHEMBL5088057 0.73 TSHR (0.37) SMN1; SMN2RAB9ATSHRKMT2ALMNA
SCHEMBL2389010 0.72 ALDH1A1 (0.33) SMN1; SMN2RAB9ATSHRKMT2AALDH1A1
SCHEMBL501046 0.71 PTGS1 (0.50) SMN1; SMN2CYP1A2KMT2AHSD17B10ALDH1A1
SCHEMBL4600179 0.70 TSHR (0.52) SMN1; SMN2RAB9ATSHRKMT2ALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 473 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260035410-A1 THERAPEUTIC PEPTIDES AND METHODS OF PEPTIDE DESIGN WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2026-02-05 US claimed
EP-4626462-A1 GLUCOCEREBROSIDASE (GBA) POLYMER CONJUGATE, PREPARATION METHOD AND USE FOR NANOTECHNOLOGICAL BASED ENZYME REPLACEMENT THERAPY Fundació Hospital Universitari Vall Hebron - Institut de Recerca (ES) 2025-10-08 EP claimed
WO-2024115612-A1 GLUCOCEREBROSIDASE (GBA) POLYMER CONJUGATE, PREPARATION METHOD AND USE FOR NANOTECHNOLOGICAL BASED ENZYME REPLACEMENT THERAPY FUNDACIÓ HOSPITAL UNIVERSITARI VALL HEBRON - INSTITUT DE RECERCA (VHIR) (ES) 2024-06-06 WO claimed
US-20230270882-A1 PEPTIDE-NANOPARTICLE CONJUGATES WISCONSIN ALUMNI RESEARCH FOUNDATION 2023-08-31 US claimed
US-11564995-B2 Peptide-nanoparticle conjugates WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2023-01-31 US claimed
CN-115087465-A Peptide-nanoparticle conjugates 威斯康星校友研究基金会 2022-09-20 CN claimed
US-20210393799-A1 DENDRITIC POLYMERS COMPLEXED WITH IMMUNE CHECKPOINT INHIBITORS FOR ENHANCED CANCER IMMUNOTHERAPY WISCONSIN ALUMNI RESEARCH FOUNDATION 2021-12-23 US claimed
CN-113613680-A Dendrimers complexed with immune checkpoint inhibitors for enhancing cancer immunotherapy 威斯康星校友研究基金会 2021-11-05 CN claimed
WO-2020092304-A9 DENDRITIC POLYMERS COMPLEXED WITH IMMUNE CHECKPOINT INHIBITORS FOR ENHANCED CANCER IMMUNOTHERAPY WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2021-07-22 WO claimed
US-20210187120-A1 PEPTIDE-NANOPARTICLE CONJUGATES WISCONSIN ALUMNI RESEARCH FOUNDATION 2021-06-24 US claimed
US-20110311990-A1 TETRANOR-PGEM/PGAM SPECIFIC IMMUNOGENS, ANTIBODIES, TRACERS, ASSAY KITS AND METHODS FOR MAKING SAME CAYMAN CHEMICAL COMPANY, INCORPORATED (US) 2011-12-22 US claimed
JP-2011528106-A 2011-11-10 JP claimed
EP-2054439-B1 CD4-RECEPTOR-DERIVED PEPTIDES AND METHOD FOR THE PREPARATION THEREOF PASTEUR INSTITUT (FR) 2011-06-01 EP claimed
EP-2318838-A1 HIGH CAPACITY SOLID PHASE Radiometer Medical ApS (DK) 2011-05-11 EP claimed
US-20110015368-A1 CD4-RECEPTOR-DERIVED PEPTIDES AND METHOD FOR THE PREPARATION THEREOF CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2011-01-20 US claimed
WO-2010006604-A1 HIGH CAPACITY SOLID PHASE RADIOMETER MEDICAL APS (DK) 2010-01-21 WO claimed
EP-2054439-A1 CD4-RECEPTOR-DERIVED PEPTIDES AND METHOD FOR THE PREPARATION THEREOF INSTITUT PASTEUR (FR) 2009-05-06 EP claimed
WO-2008015273-A1 CD4-RECEPTOR-DERIVED PEPTIDES AND METHOD FOR THE PREPARATION THEREOF INSTITUT PASTEUR (FR) 2008-02-07 WO claimed
US-7067322-B2 Fusion protein arrays on metal substrates for surface plasmon resonance imaging WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2006-06-27 US claimed
EP-0941738-B1 Antigenic conjugates of conserved lipooligosaccharides of gram negative bacteria WYETH CORP (US) 2005-05-11 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110311990-A1 TETRANOR-PGEM/PGAM SPECIFIC IMMUNOGENS, ANTIBODIES, TRACERS, ASSAY KITS AND METHODS FOR MAKING SAME PTGIR, PTGFR, PTGES SMN1; SMN2 4767/4885RAB9A 4117/4885CYP1A2 754/4885
US-20110015368-A1 CD4-RECEPTOR-DERIVED PEPTIDES AND METHOD FOR THE PREPARATION THEREOF CD4, GPR180, GPR65 SMN1; SMN2 4518/4885RAB9A 4061/4885CYP1A2 4435/4885
US-20260035410-A1 THERAPEUTIC PEPTIDES AND METHODS OF PEPTIDE DESIGN MICA, IGSF11, TNFSF10 SMN1; SMN2 1737/4885RAB9A 4281/4885CYP1A2 4516/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.