SCHEMBL6058418

SCHEMBL6058418

FC(F)=CC1CCCCC1

nearest known ligand 0.41

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
GRIK1 P39086 2/20 0.34
GRIK2 Q13002 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18745588 0.85 ALDH1A1 (0.38)
SCHEMBL9019396 0.84
SCHEMBL12321790 0.84
SCHEMBL25478332 0.78 GRIK1 (0.32) GRIK1
SCHEMBL7636887 0.78 GRIK1 (0.32) GRIK1
SCHEMBL7636890 0.78 GRIK1 (0.32) GRIK1
SCHEMBL20251097 0.77
SCHEMBL18069618 0.74
SCHEMBL5088912 0.73 GRIK1 (0.35) GRIK1GRIK2
SCHEMBL26080809 0.72 GRIK1 (0.44) GRIK1GRIK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230007940-A1 LIQUID-CRYSTAL MEDIUM COMPRISING POLYMERISABLE COMPOUNDS AND THE USE THEREOF IN LIQUID-CRYSTAL DISPLAYS MERCKP PATENT GMBH (DE) 2023-01-12 US disclosed
US-20210087469-A1 LIQUID-CRYSTALLINE MEDIUM MERCK PATENT GMBH (DE) 2021-03-25 US disclosed
US-10351771-B2 Liquid-crystalline medium MERCK PATENT GMBH (DE) 2019-07-16 US disclosed
US-9944416-B2 Filling device and use thereof for dispensing a fluid MERCK PATENT GMBH (DE) 2018-04-17 US disclosed
US-20170037316-A1 LIQUID-CRYSTALLINE MEDIUM MERCK PATENT GMBH (DE) 2017-02-09 US disclosed
CN-102557863-A Preparation method of difluoro-vinyl cyclohexane derivatives SHANGHAI SINOFLUORO SCIENT CO 2012-07-11 CN disclosed
CN-102557863-A Preparation method of difluoro-vinyl cyclohexane derivatives SHANGHAI SINOFLUORO SCIENT CO 2012-07-11 CN disclosed
US-7030283-B2 Process for producing 1,1-difluorovinyl cycloaliphatic compounds AIR PRODUCTS AND CHEMICALS, INC. (US) 2006-04-18 US disclosed
US-7030283-B2 Process for producing 1,1-difluorovinyl cycloaliphatic compounds AIR PRODUCTS AND CHEMICALS, INC. (US) 2006-04-18 US disclosed
US-20050165260-A1 Process for producing 1,1-difluorovinyl cycloaliphatic compounds VERSUM MATERIALS US, LLC 2005-07-28 US disclosed
US-20050165260-A1 Process for producing 1,1-difluorovinyl cycloaliphatic compounds VERSUM MATERIALS US, LLC 2005-07-28 US disclosed
EP-1557404-A1 Process for producing 1,1-Difluorovinyl cycloaliphatic compounds AIR PRODUCTS AND CHEMICALS, INC. (US) 2005-07-27 EP disclosed
EP-1557404-A1 Process for producing 1,1-Difluorovinyl cycloaliphatic compounds AIR PRODUCTS AND CHEMICALS, INC. (US) 2005-07-27 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170037316-A1 LIQUID-CRYSTALLINE MEDIUM FES, NEFM, SOST GRIK1 2625/4885GRIK2 3982/4885
US-20050165260-A1 Process for producing 1,1-difluorovinyl cycloaliphatic compounds KMO, KCNB1, KCNB2 GRIK1 129/4885GRIK2 225/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.