Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HNF4A | P41235 | 1/20 | 0.69 |
| ▸ | MYC | P01106 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | FABP3 | P05413 | 1/20 | 0.53 |
| ▸ | FABP4 | P15090 | 1/20 | 0.53 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.53 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | GFER | P55789 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL225203 | 0.90 | HNF4A (0.71) | HNF4AMYCALDH1A1L3MBTL1LMNA | |
| SCHEMBL5089936 | 0.88 | ALDH1A1 (0.66) | HNF4AMYCALDH1A1L3MBTL1LMNA | |
| SCHEMBL7407371 | 0.87 | HNF4A (0.73) | HNF4AMYCALDH1A1L3MBTL1LMNA | |
| SCHEMBL87965 | 0.86 | HNF4A (0.71) | HNF4AMYCALDH1A1L3MBTL1LMNA | |
| Benzene SCHEMBL28480917 | 0.85 | HNF4A (0.69) | HNF4AMYCALDH1A1FABP3FABP4 | |
| SCHEMBL133057 | 0.85 | HNF4A (0.69) | HNF4AMYCALDH1A1FABP3FABP4 | |
| SCHEMBL26624744 | 0.85 | HNF4A (0.69) | HNF4AMYCALDH1A1FABP3FABP4 | |
| Benzene SCHEMBL1403559 | 0.85 | HNF4A (0.69) | HNF4AMYCALDH1A1FABP3FABP4 | |
| Hydrochloric Acid SCHEMBL28366748 | 0.84 | HNF4A (0.69) | HNF4AMYCALDH1A1L3MBTL1LMNA | |
| SCHEMBL87757 | 0.84 | HNF4A (0.69) | HNF4AMYCALDH1A1L3MBTL1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10266737-B2 | Adsorption systems using metal-organic frameworks | ARKEMA INC. (US) | 2019-04-23 | — | — | US | disclosed |
| US-20150291870-A1 | ADSORPTION SYSTEMS USING METAL-ORGANIC FRAMEWORKS | ARKEMA INC. | 2015-10-15 | — | — | US | disclosed |
| EP-2885365-A2 | ADSORPTION SYSTEMS USING METAL-ORGANIC FRAMEWORKS | Arkema, Inc. (US) | 2015-06-24 | — | — | EP | disclosed |
| WO-2014028574-A9 | ADSORPTION SYSTEMS USING METAL-ORGANIC FRAMEWORKS | ARKEMA INC. (US) | 2015-04-02 | — | — | WO | disclosed |
| WO-2014028574-A2 | ADSORPTION SYSTEMS USING METAL-ORGANIC FRAMEWORKS | ARKEMA INC. (US) | 2014-02-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150291870-A1 | ADSORPTION SYSTEMS USING METAL-ORGANIC FRAMEWORKS | PFAS, CHIA, PARN | HNF4A 457/4885MYC 2372/4885ALDH1A1 1737/4885 |
| US-10266737-B2 | Adsorption systems using metal-organic frameworks | PFAS, CHIA, PARN | HNF4A 457/4885MYC 2372/4885ALDH1A1 1737/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.