Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 3/20 | 0.59 |
| ▸ | POLH | Q9Y253 | 8/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.58 |
| ▸ | POLB | P06746 | 3/20 | 0.58 |
| ▸ | APEX1 | P27695 | 3/20 | 0.58 |
| ▸ | RECQL | P46063 | 3/20 | 0.58 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.58 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.57 |
| ▸ | CA12 | O43570 | 5/20 | 0.57 |
| ▸ | CA7 | P43166 | 5/20 | 0.57 |
| ▸ | CA4 | P22748 | 4/20 | 0.57 |
| ▸ | TYR | P14679 | 3/20 | 0.57 |
| ▸ | CBS | P35520 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.56 |
| ▸ | MMP1 | P03956 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3404530 | 0.95 | AKR1B1 (0.64) | AKR1B1POLHCYP3A4KDM4ECYP2D6 | |
| SCHEMBL31287228 | 0.94 | EPHX2 (0.63) | AKR1B1POLHCYP3A4KDM4ECYP2D6 | |
| SCHEMBL17938761 | 0.90 | CYP3A4 (0.61) | AKR1B1POLHCYP3A4KDM4ECYP2D6 | |
| SCHEMBL3989919 | 0.89 | NOX4 (0.59) | AKR1B1POLHCYP3A4KDM4ECYP2D6 | |
| SCHEMBL8442485 | 0.87 | POLH (0.64) | AKR1B1POLHCYP3A4KDM4ECYP2D6 | |
| Kaempferol SCHEMBL5090719 | 0.82 | MEN1 (0.67) | AKR1B1POLHCYP3A4KDM4ECYP2D6 | |
| SCHEMBL3985496 | 0.80 | MEN1 (0.64) | AKR1B1POLHCYP3A4KDM4ECYP2D6 | |
| SCHEMBL13973823 | 0.80 | AKR1B1 (0.93) | AKR1B1CYP3A4KDM4ECYP2D6POLB | |
| SCHEMBL16131012 | 0.80 | AKR1B1 (0.93) | AKR1B1CYP3A4KDM4ECYP2D6POLB | |
| SCHEMBL13963384 | 0.80 | AKR1B1 (0.93) | AKR1B1CYP3A4KDM4ECYP2D6POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2001304-A2 | EXTRACTIONS AND METHODS COMPRISING ELDER SPECIES | Herbalscience Singapore Pte. Ltd. (US) | 2008-12-17 | — | — | EP | disclosed |
| WO-2007109600-A2 | EXTRACTIONS AND METHODS COMPRISING ELDER SPECIES | HERBALSCIENCE SINGAPORE PTE. LTD. (US) | 2007-09-27 | — | — | WO | disclosed |