Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | ERN1 | O75460 | 3/20 | 0.32 |
| ▸ | TLR2 | O60603 | 1/20 | 0.32 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.32 |
| ▸ | TLR6 | Q9Y2C9 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | IAPP | P10997 | 1/20 | 0.31 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.31 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL986274 | 0.80 | ERN1 (0.55) | BACE1ALOX5ERN1TLR2TLR1 | |
| SCHEMBL10071683 | 0.79 | ALOX5 (0.42) | BACE1ALOX5POLBRAB9AABCB1 | |
| SCHEMBL199801 | 0.78 | GABRA1 (0.42) | ALOX12ALDH1A1 | |
| SCHEMBL19782076 | 0.72 | ALDH1A1 (0.56) | ERN1POLBGAARAB9AALOX12 | |
| SCHEMBL14337060 | 0.72 | SIRT2 (0.51) | POLBRAB9AALDH1A1 | |
| SCHEMBL14899338 | 0.72 | ERN1 (0.60) | ERN1POLBGAARAB9AIAPP | |
| SCHEMBL5090901 | 0.72 | GABRA1 (0.43) | ERN1TLR2TLR1TLR6POLB | |
| SCHEMBL2834212 | 0.72 | ALDH1A1 (0.52) | ERN1POLBGAARAB9AIAPP | |
| SCHEMBL31550782 | 0.72 | ALDH1A1 (0.52) | ERN1POLBGAARAB9AIAPP | |
| SCHEMBL20809969 | 0.68 | MAPT (0.46) | POLBRAB9AALOX12ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10597377-B2 | Somatostatin modulators and uses thereof | Crinetics Pharmaceuticals, Inc. (US) | 2020-03-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10597377-B2 | Somatostatin modulators and uses thereof | SSTR5, SSTR2, SSTR4 | BACE1 1287/4885ALOX5 1239/4885ERN1 2959/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.