SCHEMBL509227

SCHEMBL509227

C=C(C)C1=NC(C)(CCCCCCCCCCCC)C(=O)O1

nearest known ligand 0.34

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
SIRT2 Q8IXJ6 1/20 0.31
PTPN1 P18031 4/20 0.31
ACP1 P24666 3/20 0.31
CDC25B P30305 3/20 0.31
CPT1A P50416 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL507992 0.75 CPT1A (0.37) CPT1A
SCHEMBL27990757 0.62 PTPN1 (0.34) SIRT2PTPN1ACP1CDC25BCPT1A
SCHEMBL25205553 0.62 SIRT2 (0.38) SIRT2PTPN1ACP1CDC25B
SCHEMBL8920856 0.62 SIRT2 (0.38) SIRT2PTPN1ACP1CDC25B
SCHEMBL11042527 0.62 PRKCA (0.33)
SCHEMBL1023054 0.60 MMP2 (0.38) SIRT2CPT1A
SCHEMBL1023716 0.60 MMP2 (0.38) SIRT2CPT1A
SCHEMBL1023104 0.60 MMP2 (0.38) SIRT2CPT1A
SCHEMBL14119928 0.58 SIRT2 (0.39) SIRT2PTPN1ACP1CDC25BCPT1A
SCHEMBL21958419 0.57 MMP2 (0.41) SIRT2PTPN1ACP1CDC25BCPT1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 286 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12285922-B2 Method for making photofunctional contact lenses ALCON INC. (CH) 2025-04-29 US claimed
US-12111443-B2 Method for making photochromic contact lenses ALCON INC. (CH) 2024-10-08 US claimed
EP-4313567-A1 METHOD FOR MAKING PHOTOCHROMIC CONTACT LENSES Alcon Inc. (CH) 2024-02-07 EP claimed
EP-4304842-A1 METHOD FOR MAKING PHOTOFUNCTIONAL CONTACT LENSES Alcon Inc. (CH) 2024-01-17 EP claimed
EP-4304843-A1 METHOD FOR MAKING PHOTOCHROMIC CONTACT LENSES Alcon Inc. (CH) 2024-01-17 EP claimed
US-11833771-B2 Method for making photochromic contact lenses ALCON INC. (CH) 2023-12-05 US claimed
EP-3976362-B1 METHOD FOR MAKING OPAQUE COLORED SILICONE HYDROGEL CONTACT LENSES ALCON INC (CH) 2023-06-07 EP claimed
US-11584097-B2 Method for making opaque colored silicone hydrogel contact lenses ALCON INC. (CH) 2023-02-21 US claimed
US-20220339895-A1 METHOD FOR MAKING PHOTOCHROMIC CONTACT LENSES ALCON INC. (CH) 2022-10-27 US claimed
WO-2022208450-A1 METHOD FOR MAKING PHOTOCHROMIC CONTACT LENSES ALCON INC. (CH) 2022-10-06 WO claimed
US-20110134387-A1 SILICONE HYDROGEL LENS WITH A COVALENTLY ATTACHED COATING ALCON INC. (CH) 2011-06-09 US claimed
EP-0784063-B1 Method for making azlactone-functional homopolymers and method for making an article made of a thermoplastic polymer blended with an azlactone-functional homopolymer MINNESOTA MINING & MFG (US) 2000-03-01 EP claimed
US-5840106-A CONTAINS DISPERSANT FORMED FROM THE REACTION PRODUCT OF AN ALKENYL AZLACTONE WITH AN N-SUBSTITUTED AMINO ACID COMPOUND; REACTION PRODUCT IS RING-OPENED USING AN AMINE MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1998-11-24 US claimed
EP-0721483-B1 AZLACTONE-FUNCTIONAL HOMOPOLYMER BLENDS, ARTICLES PRODUCED THEREFROM MINNESOTA MINING & MFG (US) 1998-11-11 EP claimed
EP-0784063-A2 Azlactone-functional polymer blends, articles produced therefrom and methods for preparing both MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1997-07-16 EP claimed
EP-0644904-B1 SUPPORTS HAVING AZLACTONE-FUNCTIONAL SURFACES, ADDUCT SUPPORTS, AND METHODS OF PREPARING SAME MINNESOTA MINING & MFG (US) 1997-07-16 EP claimed
US-5408002-A Blending with thermoplastic polymers; medical diagnostic equipment MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1995-04-18 US claimed
WO-1993025594-A1 SUPPORTS HAVING AZLACTONE-FUNCTIONAL SURFACES, ADDUCT SUPPORTS, AND METHODS OF PREPARING SAME MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1993-12-23 WO claimed
US-5262484-A Free radical grafting to addition polymers; surface treatment with nucleophilic agents; adhesion properties for binding, immobilizing proteins; immunoassay MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1993-11-16 US claimed
US-5013795-A Azlactone graft copolymers MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1991-05-07 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11584097-B2 Method for making opaque colored silicone hydrogel contact lenses COIL, CRYAB, CRYAA SIRT2 361/4885PTPN1 4731/4885ACP1 4511/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.