SCHEMBL509235

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL508372	0.93	KCNH2 (0.54)	KCNH2ENPP3ALPLENPP1XIAP
	SCHEMBL4805481	0.82	KCNH2 (0.70)	KCNH2MEN1MAPTALOX12KMT2A
	SCHEMBL4718347	0.82	KCNH2 (0.54)	KCNH2ENPP3ALPLENPP1XIAP
	SCHEMBL5228264	0.77	KCNH2 (0.49)	KCNH2ENPP3ALPLENPP1XIAP
	SCHEMBL14303593	0.75	KCNH2 (0.59)	KCNH2ENPP3ALPLENPP1XIAP
	SCHEMBL5176401	0.75	KCNH2 (0.47)	KCNH2ENPP3ALPLENPP1XIAP
	SCHEMBL509165	0.73	KCNH2 (0.58)	KCNH2ENPP3ALPLENPP1XIAP
	SCHEMBL4911915	0.72	KCNH2 (0.33)	KCNH2GAAALDH1A1POLBCYP3A4
	SCHEMBL508842	0.72	KCNH2 (0.67)	KCNH2MEN1MAPTALOX12KMT2A
	SCHEMBL508704	0.69	KCNH2 (0.52)	KCNH2ENPP3ALPLENPP1XIAP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.