Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 7/20 | 0.56 |
| ▸ | MMP9 | P14780 | 7/20 | 0.56 |
| ▸ | MMP13 | P45452 | 7/20 | 0.56 |
| ▸ | MMP7 | P09237 | 6/20 | 0.56 |
| ▸ | ADAM17 | P78536 | 5/20 | 0.56 |
| ▸ | ADAM10 | O14672 | 1/20 | 0.56 |
| ▸ | MMP8 | P22894 | 1/20 | 0.56 |
| ▸ | MMP14 | P50281 | 1/20 | 0.56 |
| ▸ | MMP2 | P08253 | 5/20 | 0.50 |
| ▸ | MMP3 | P08254 | 5/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4926651 | 1.00 | MMP1 (0.56) | MMP1MMP9MMP13MMP7ADAM17 | |
| SCHEMBL14045734 | 0.84 | SLC1A2 (0.46) | MMP1MMP9MMP13MMP7ADAM17 | |
| SCHEMBL4929339 | 0.82 | ALDH1A1 (0.42) | MMP1MMP9MMP13MMP7ADAM17 | |
| SCHEMBL1443796 | 0.81 | MMP9 (0.54) | MMP1MMP9MMP13MMP7ADAM17 | |
| SCHEMBL5180159 | 0.81 | MMP9 (0.54) | MMP1MMP9MMP13MMP7ADAM17 | |
| SCHEMBL1443795 | 0.81 | MMP9 (0.54) | MMP1MMP9MMP13MMP7ADAM17 | |
| SCHEMBL5182133 | 0.80 | MMP9 (0.53) | MMP1MMP9MMP13MMP7ADAM17 | |
| SCHEMBL14025839 | 0.80 | MMP9 (0.60) | MMP1MMP9MMP13MMP7ADAM17 | |
| SCHEMBL4916984 | 0.80 | MMP9 (0.60) | MMP1MMP9MMP13MMP7ADAM17 | |
| SCHEMBL4926953 | 0.80 | MMP1 (0.58) | MMP1MMP9MMP13MMP7ADAM17 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2008508348-A | — | — | 2008-03-21 | — | — | JP | claimed |
| EP-1796681-A2 | COMPOUNDS FOR INHIBITING COPPER-CONTAINING AMINE OXIDASES AND USES THEREOF | Genmedica Therapeutics SL (ES) | 2007-06-20 | — | — | EP | claimed |
| WO-2006013209-A2 | COMPOUNDS FOR INHIBITING COPPER-CONTAINING AMINE OXIDASES AND USES THEREOF | GENMEDICA THERAPEUTICS SL (ES) | 2006-02-09 | — | — | WO | claimed |
| EP-1796681-A2 | COMPOUNDS FOR INHIBITING COPPER-CONTAINING AMINE OXIDASES AND USES THEREOF | Genmedica Therapeutics SL (ES) | 2007-06-20 | — | — | EP | disclosed |
| WO-2006013209-A2 | COMPOUNDS FOR INHIBITING COPPER-CONTAINING AMINE OXIDASES AND USES THEREOF | GENMEDICA THERAPEUTICS SL (ES) | 2006-02-09 | — | — | WO | disclosed |